Kinetics, of photobleaching of Radachlorin® photosensitizer in aqueous solutions

被引：19

作者：

Beltukova, D. M. ^{[1
,2
]}

Semenova, I. V. ^{[1
]}

Smolin, A. G. ^{[1
]}

Vasyutinskii, O. S. ^{[1
]}

机构：

[1] Ioffe Inst, Polytekhn Skaya 26, St Petersburg 194021, Russia

[2] Peter Great St Petersburg Polytech Univ, Polytekhn Skaya 29, St Petersburg 195251, Russia

来源：

CHEMICAL PHYSICS LETTERS | 2016年 / 662卷

基金：

俄罗斯科学基金会;

关键词：

SINGLET OXYGEN LUMINESCENCE; PHOTODYNAMIC THERAPY; CHLORIN; SENSITIZER; PARAMETERS; EFFICACY; TIME;

D O I：

10.1016/j.cplett.2016.09.035

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Kinetics of Radachlorin photosensitizer fluorescence in aqueous solution excited by CW laser radiation at 405 nm has been studied. Interpretation of the experimental results was based on numerical solution of a set of rate equations. Rate constants of possible bleaching mechanisms were determined and an electron transfer reaction between triplet state photosensitizer and oxygen molecules was found to be the main bleaching mechanism. The fluorescence intensity was almost independent of the oxygen concentration indicating that the triplet state degradation occurs mainly in collisions with oxygen molecules. The results obtained can be utilized for providing optimal conditions for singlet oxygen generation. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：127 / 131

页数：5

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