Maternal mortality and severe maternal morbidity from acute fatty liver of pregnancy in the Netherlands

被引：39
作者：
Dekker, Ruth R. [1 ,2 ]
Schutte, Joke M. [2 ]
Stekelenburg, Jelle [3 ]
Zwart, Joost J. [4 ]
van Roosmalen, Jos [4 ,5 ]
机构：
[1] Univ Groningen, Univ Med Ctr Groningen, Dept Obstet & Gynaecol, NL-9700 RB Groningen, Netherlands
[2] Isola Klin Zwolle, Dept Obstet & Gynaecol, Zwolle, Netherlands
[3] Med Ctr Leeuwarden, Dept Obstet & Gynaecol, Leeuwarden, Netherlands
[4] Leiden Univ, Med Ctr, Dept Obstet, Leiden, Netherlands
[5] Vrije Univ Amsterdam, Med Ctr, EMGO Inst Hlth & Care Res, Dept Med Humanities, Amsterdam, Netherlands
来源：
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2011年 / 157卷 / 01期
关键词：
Acute fatty liver of pregnancy; Maternal mortality; Maternal morbidity; DISEASE; PREECLAMPSIA;
D O I：
10.1016/j.ejogrb.2011.02.015
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To assess maternal death and severe maternal morbidity from acute fatty liver of pregnancy (AFLP) in the Netherlands. Study design: A retrospective study of all cases of maternal mortality in the Netherlands between 1983 and 2006 and all cases of severe maternal morbidity in the Netherlands between 2004 and 2006, in which all 98 maternity units in the Netherlands participated. Maternal mortality ratio (MMR) and incidence of severe maternal morbidity were the main outcome measures. Results: The MMR from direct maternal mortality from AFLP was 0.13 per 100,000 live births (95% CI 0.05-0.29). The incidence of severe maternal morbidity from AFLP was 3.2 per 100,000 deliveries (95% CI 1.8-5.7). Conclusions: AFLP is a rare condition which still causes severe maternal morbidity and in some cases mortality. Referral to a tertiary care hospital for treatment of this uncommon disease should be considered. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：27 / 31
页数：5
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