Acute Motor-dominant Polyneuropathy as Guillain-Barre Syndrome and Multiple Mononeuropathies in a Patient with Sjogren's Syndrome

被引:9
作者
Tanaka, Kenichiro [1 ]
Nakayasu, Hiroyuki [1 ]
Suto, Yutaka [1 ]
Takahashi, Shotaro [1 ]
Konishi, Yoshihiro [2 ]
Nishimura, Hirotake [3 ]
Ueno, Rino [4 ]
Kusunoki, Susumu [4 ]
Nakashima, Kenji [5 ]
机构
[1] Tottori Prefectural Cent Hosp, Dept Neurol, Tottori, Tottori, Japan
[2] Tottori Med Ctr, Dept Clin Res, Tottori, Tottori, Japan
[3] Kawasaki Univ, Fac Med, Dept Pathol, Kawasaki, Kanagawa, Japan
[4] Kinki Univ, Fac Med, Dept Neurol, Higashiosaka, Osaka, Japan
[5] Tottori Univ, Fac Med, Dept Brain & Neurosci, Div Neurol, Tottori, Tottori, Japan
关键词
Sjogren's syndrome; Guillain-Barre syndrome; antiganglioside antibody; NEUROPATHY; MANIFESTATIONS; ANTIBODIES;
D O I
10.2169/internalmedicine.55.6881
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A patient with xerostomia and xerophthalmia due to Sjogren's syndrome presented with acute motor-dominant polyneuropathy and multiple mononeuropathy with antiganglioside antibodies. Nerve conduction studies and a sural nerve biopsy revealed the neuropathy as a mixture of segmental demyelination and axonal degeneration. Positive results were obtained for several antiganglioside antibodies. Corticosteroid treatment proved effective. The neuropathy was considered to represent a mixture of polyneuropathy as Guillain-Barre syndrome and multiple mononeuropathy via Sjogren's syndrome. We speculate that Guillain-Barre syndrome occurred in the patient and Guillain-Barre syndrome itself activated multiple mononeuropathy via Sjogren's syndrome.
引用
收藏
页码:2717 / 2722
页数:6
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