Association of celiac disease in patients with multiple sclerosis in Tuscany

被引：1
|
作者：
Piccini, Barbara [1 ]
Ulivelli, Monica [2 ]
Amato, Maria Pia [3 ]
Bartalini, Sabina [4 ]
Falcini, Mario [5 ]
Giannini, Marta [3 ]
Magnani, Eliana [6 ]
Massacesi, Luca [7 ]
Repice, Anna Maria [6 ]
Vascotto, Marina [8 ]
Grosso, Salvatore [9 ]
机构：
[1] Meyer Childrens Hosp, Tuscany Reg Ctr Pediat Diabet, Pediat Dept, Florence, Italy
[2] Univ Siena, Ctr Multiple Sclerosis, Neurol & Neurophysiopathol Dept, Siena, Italy
[3] Univ Florence, Dept NEUROFARBA, Sect Neurosci, Florence, Italy
[4] Univ Hosp Santa Maria Scotte, Ctr Multiple Sclerosis, Neurol & Neurophysiopathol Dept, Siena, Italy
[5] Santo Stefano Hosp, Neurol Dept, Prato, Italy
[6] Univ Florence, Careggi Univ Hosp, Dept Neurosci 2, Florence, Italy
[7] Univ Florence, Careggi Univ Hosp, Dept Neurosci, Florence, Italy
[8] Univ Hosp Santa Maria Scotte, Dept Pediat, Clin Pediat, Siena, Italy
[9] Univ Siena, Dept Pediat, Clin Pediat, Siena, Italy
来源：
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS | 2020年 / 112卷 / 06期
关键词：
Celiac disease; Multiple sclerosis; Epidemiology; Comorbidity; GLUTEN;
D O I：
10.17235/reed.2020.6123/2018
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Background and study purpose: to describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: the association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: the frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population (0.6 % vs 1 %) (p = 0.65).
引用
收藏
页码：474 / 476
页数：3
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