Total Synthesis and Complete Structural Assignment of Thiocillin I

被引：48

作者：

Aulakh, Virender S. ^{[1
]}

Ciufolini, Marco A. ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 15期

基金：

加拿大自然科学与工程研究理事会;

关键词：

TOXIC CYCLIC-PEPTIDES; ONE-POT; DIPHENYLPHOSPHORYL AZIDE; THIOPEPTIDE ANTIBIOTICS; ORGANIC-SYNTHESIS; PATELLAMIDES-B; BRONSTED ACID; 1ST SYNTHESIS; AMINO-ACIDS; ALDEHYDES;

D O I：

10.1021/ja110166x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The total synthesis of the thiopeptide antibiotic, thiocillin I, is described. This work unequivocally defines the full structure (constitution and configuration) of the natural product as 1.

引用

页码：5900 / 5904

页数：5

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