The Essential β-Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

被引:60
作者
Rossiter, Amanda E. [1 ]
Leyton, Denisse L. [1 ]
Tveen-Jensen, Karina [1 ]
Browning, Douglas F. [1 ]
Sevastsyanovich, Yanina [1 ]
Knowles, Timothy J. [2 ]
Nichols, Katie B. [3 ]
Cunningham, Adam F. [1 ]
Overduin, Michael [2 ]
Schembri, Mark A. [3 ]
Henderson, Ian R. [1 ]
机构
[1] Univ Birmingham, Sch Immun & Infect, Birmingham B15 2TT, W Midlands, England
[2] Univ Birmingham, Sch Canc Sci, Birmingham B15 2TT, W Midlands, England
[3] Univ Queensland, Sch Chem & Mol Biosci, Brisbane, Qld, Australia
基金
英国生物技术与生命科学研究理事会;
关键词
OUTER-MEMBRANE PROTEIN; ESCHERICHIA-COLI; RESONANCE ASSIGNMENTS; SECONDARY STRUCTURE; YAET COMPLEX; IDENTIFICATION; SECRETION; MECHANISMS; BACTERIA; REVEALS;
D O I
10.1128/JB.00192-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Autotransporter biogenesis is dependent upon BamA, a central component of the beta-barrel assembly machinery (BAM) complex. In this report, we detail the role of the other BAM components (BamB-E). We identify the importance of BamD in autotransporter biogenesis and show that BamB, BamC, and BamE are not required.
引用
收藏
页码:4250 / 4253
页数:4
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