共 214 条
Origin, Development, and Synaptogenesis of Cortical Interneurons
被引:23
作者:

Llorca, Alfredo
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Edinburgh, Ctr Discovery Brain Sci, Sch Biomed Sci, Visual Neurosci Lab, Edinburgh, Scotland Univ Edinburgh, Ctr Discovery Brain Sci, Sch Biomed Sci, Visual Neurosci Lab, Edinburgh, Scotland

Deogracias, Ruben
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h-index: 0
机构:
Univ Salamanca, Inst Neurosci Castilla & Leon INCyL, Neuronal Circuits Format & Brain Disorders Lab, Salamanca, Spain
Inst Biomed Res Salamanca, Salamanca, Spain
Univ Salamanca, Sch Med, Dept Cell Biol & Pathol, Salamanca, Spain Univ Edinburgh, Ctr Discovery Brain Sci, Sch Biomed Sci, Visual Neurosci Lab, Edinburgh, Scotland
机构:
[1] Univ Edinburgh, Ctr Discovery Brain Sci, Sch Biomed Sci, Visual Neurosci Lab, Edinburgh, Scotland
[2] Univ Salamanca, Inst Neurosci Castilla & Leon INCyL, Neuronal Circuits Format & Brain Disorders Lab, Salamanca, Spain
[3] Inst Biomed Res Salamanca, Salamanca, Spain
[4] Univ Salamanca, Sch Med, Dept Cell Biol & Pathol, Salamanca, Spain
关键词:
brain;
cortex;
interneuron;
development;
synaptogenesis;
neuron;
cell death;
CAUDAL GANGLIONIC EMINENCE;
VENTRAL TELENCEPHALIC PROGENITORS;
GABAERGIC INTERNEURONS;
CEREBRAL-CORTEX;
TANGENTIAL MIGRATION;
INHIBITORY INTERNEURONS;
NEUROTROPHIC FACTOR;
PERISOMATIC INHIBITION;
NEURONAL-ACTIVITY;
NMDA RECEPTORS;
D O I:
10.3389/fnins.2022.929469
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
The mammalian cerebral cortex represents one of the most recent and astonishing inventions of nature, responsible of a large diversity of functions that range from sensory processing to high-order cognitive abilities, such as logical reasoning or language. Decades of dedicated study have contributed to our current understanding of this structure, both at structural and functional levels. A key feature of the neocortex is its outstanding richness in cell diversity, composed by multiple types of long-range projecting neurons and locally connecting interneurons. In this review, we will describe the great diversity of interneurons that constitute local neocortical circuits and summarize the mechanisms underlying their development and their assembly into functional networks.
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