Outcome of prenatal diagnosis of clubfoot: a single institution experience

Aim: To assess the accuracy of antenatal diagnosis of clubfoot (CF), risk factors and outcomes in postnatal. Patients & methods: Maternal characteristics, sonographic signs and postnatal outcomes were evaluated in 60 patients with a prenatal diagnosis of CF between 2007 and 2020. Results: The rate of antenatal diagnosis of CF was 3.72/1000 live births. The false-positive rate was 6.67%. 66.7% of fetuses had bilateral CF and 33.3% had unilateral CF; 58.3% were isolated and 41.7% were complex; 58.3% were males and 41.7% were female; 16.7% were multiple pregnancies and 10% were cases of consanguinity. Conclusion: The accuracy of the diagnosis of CF depends on the operator's skills. A significant relationship is demonstrated between the interruption of pregnancy, consanguinity, laterality and complexity. Lay abstract: CF is one of the most common fetal anomalies detected antenatally on ultrasound, occurring in approximately 1/1000 live births. We present our single institution experience with the antenatal diagnosis of CF. Over 60 cases, the rate of prenatal diagnosis of CF was 3.72/1000 live births; of which 33.3% had unilateral CF; 58.3% were isolated and 41.7% were complex; 58.3% were males and 41.7% were female; 16.7% were multiple pregnancies and 10% were cases of consanguinity.