Impact of IgG oligomerization state on the potency of complement-dependent cytotoxicity

被引：0
|
作者：
Beurskens, Frank J. [1 ]
de Jong, Rob N. [1 ]
Wang, Guanbo [2 ,3 ,4 ]
Voorhorst, Marleen [1 ]
van den Bremer, Ewald T. J. [1 ]
Labrijn, Aran F. [1 ]
Schuurman, Janine [1 ]
Heck, Albert J. R. [2 ,3 ,4 ]
Parren, Paul W. H. I. [1 ,5 ]
机构：
[1] Genmab, Utrecht, Netherlands
[2] Univ Utrecht, Biomol Mass Spectrometry & Prote, Bijvoet Ctr Biomol Res, NL-3508 TC Utrecht, Netherlands
[3] Univ Utrecht, Utrecht Inst Pharmaceut Sci, NL-3508 TC Utrecht, Netherlands
[4] Netherlands Prote Ctr, Utrecht, Netherlands
[5] Leiden Univ, Med Ctr, Dept Immunohematol & Blood Transfus, Leiden, Netherlands
来源：
IMMUNOBIOLOGY | 2016年 / 221卷 / 10期
关键词：
D O I：
10.1016/j.imbio.2016.06.044
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
29
引用
收藏
页码：1143 / 1144
页数：2
相关论文
共 50 条
  • [1] Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity
    Quast, Isaak
    Keller, Christian W.
    Maurer, Michael A.
    Giddens, John P.
    Tackenberg, Bjoern
    Wang, Lai-Xi
    Muenz, Christian
    Nimmerjahn, Falk
    Dalakas, Marinas C.
    Luenemann, Jan D.
    JOURNAL OF CLINICAL INVESTIGATION, 2015, 125 (11): : 4160 - 4170
  • [2] CONVERSION OF IGG-MEDIATED COMPLEMENT-DEPENDENT CYTOTOXICITY BY REDUCING REAGENTS
    MCINTYRE, JA
    BOLDT, HD
    FAULK, WP
    HALBROOK, H
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 1991, 10 (01): : 117 - 124
  • [3] Neuron-derived IgG Protects Neurons from Complement-dependent Cytotoxicity
    Zhang, Jie
    Niu, Na
    Li, Bingjie
    McNutt, Michael A.
    JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2013, 61 (12) : 869 - 879
  • [4] Regulation of complement-dependent cytotoxicity by microRNA
    Hillman, Y.
    Shomron, N.
    Fishelson, Z.
    MOLECULAR IMMUNOLOGY, 2013, 56 (03) : 263 - 263
  • [5] COMPLEMENT-DEPENDENT CYTOTOXICITY OF A MURINE SARCOMA
    FULLER, TC
    FEDERATION PROCEEDINGS, 1972, 31 (02) : A785 - &
  • [6] Regulation of complement-dependent cytotoxicity by microRNAs
    Hillman, Yaron
    Shomron, Noam
    Fishelson, Zvi
    IMMUNOBIOLOGY, 2016, 221 (10) : 1181 - 1181
  • [7] Discovery of microRNAs regulating complement-dependent cytotoxicity
    Hillman, Yaron
    Mardamshina, Mariya
    Geiger, Tamar
    Shomron, Noam
    Fishelson, Zvi
    MOLECULAR IMMUNOLOGY, 2017, 89 : 150 - 150
  • [8] Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells
    Dantas, Ezequiel
    Erra Diaz, Fernando
    Gerber, Pehuen Pereyra
    Merlotti, Antonela
    Varese, Augusto
    Ostrowski, Matias
    Sabatte, Juan
    Geffner, Jorge
    ONCOTARGET, 2016, 7 (45) : 74203 - 74216
  • [9] Multiple Sclerosis Oligoclonal Bands Contain IgG Aggregates and Induce Complement-dependent Neuronal Cytotoxicity
    Alvarez, Enrique
    Zhou, Wenbo
    Graner, Michael
    Yu, Xiaoli
    MULTIPLE SCLEROSIS JOURNAL, 2023, 29 : 826 - 827
  • [10] Belatacept does not mediate complement-dependent cytotoxicity or antibody-dependent cellular cytotoxicity
    Davis, Patricia M.
    Nadler, Steven G.
    Suchard, Suzanne J.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2008, 8 : 619 - 619
12345