Synthesis and Cross-Coupling of Sulfonamidomethyltrifluoroborates

被引：29

作者：

Molander, Gary A. ^{[1
]}

Fleury-Bregeot, Nicolas ^{[1
]}

Hiebel, Marie-Aude ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, Philadelphia, PA 19104 USA

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 07期

关键词：

HALO BORONIC ESTERS; SULFONAMIDES; DISCOVERY; POTENT; AMINOMETHYLATIONS; DERIVATIVES; ANTICANCER; ALKYL;

D O I：

10.1021/ol200202g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfonamidomethyltrifluoroborates were successfully synthesized and cross-coupled with a wide range of aryl and heteroaryl chlorides, allowing the construction of a sulfonamidomethyl aryl linkage through a new disconnection, thus offering a new way to access such structurally interesting motifs.

引用

页码：1694 / 1697

页数：4

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