Current Staging and Prognostic Factors in Melanoma

被引：46

作者：

Bartlett, Edmund K. ^{[1
]}

Karakousis, Giorgos C. ^{[1
]}

机构：

[1] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2015年 / 24卷 / 02期

关键词：

Melanoma; Staging; Prognosis; Sentinel lymph node; Prognostic factors; LYMPH-NODE BIOPSY; PRIMARY CUTANEOUS MELANOMA; AMERICAN JOINT COMMITTEE; VERTICAL GROWTH-PHASE; TUMOR-INFILTRATING LYMPHOCYTES; I MALIGNANT-MELANOMA; THIN MELANOMA; SENTINEL-NODE; MITOTIC RATE; EUROPEAN ORGANIZATION;

D O I：

10.1016/j.soc.2014.12.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The current American Joint Commission for Cancer staging system for melanoma includes thickness, ulceration, and mitotic index as primary tumor factors for patients with stage I and II disease. Number and size of nodal metastases, presence of satellitosis and in-transit disease, and tumor ulceration status categorize patients with stage Ill disease. Presence and location of distant metastatic disease and increased lactate dehydrogenase level stratify prognosis in patients with stage IV disease. Factors predictive of sentinel lymph node positivity are also studied, particularly in patients with T1 melanomas, but are not always congruent with those predictive of survival.

引用

页码：215 / +

页数：14

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