Colistin heteroresistance in Acinetobacter and its association with previous colistin therapy

被引：161
作者：
Hawley, Joshua S. [1 ]
Murray, Clinton K. [1 ]
Jorgensen, James H. [2 ]
机构：
[1] Brooke Army Med Ctr, Dept Med, Ft Sam Houston, TX 78234 USA
[2] Univ Texas Hlth Sci Ctr San Antonio, Dept Pathol, San Antonio, TX 78229 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 01期
关键词：
D O I：
10.1128/AAC.00766-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Colistin heteroresistance has been reported among Acinetobacter isolates; however, its association with prior colistin therapy has not been not described. A population analysis profile identified resistant Acinetobacter subpopulations from colistin-susceptible clinical isolates. The proportion of cells exhibiting heteroresistance was significantly higher among isolates recovered from patients treated with colistin.
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页码：351 / 352
页数：2
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