Solvent-free synthesis of functionalized flavones under microwave irradiation

被引：110
|
作者：
Seijas, JA [1 ]
Vázquez-Tato, MP [1 ]
Carballido-Reboredo, R [1 ]
机构：
[1] Univ Santiago de Compostela, Fac Ciencias, Dept Quim Organ, Lugo 27080, Spain
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 07期
关键词：
D O I：
10.1021/jo048685z
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Eco-friendly direct solvent-free synthesis of flavones is achieved by microwave irradiation of phloroglucinol and beta-ketoesters. Heating with microwaves versus under classical conditions was shown to be higher yielding, cleaner, and faster. The reaction goes through a cycloaddition of an alpha-oxo ketene intermediate followed by an uncatalyzed thermal Fries rearrangement.
引用
收藏
页码：2855 / 2858
页数：4
相关论文
共 50 条
  • [1] Solvent-free synthesis of melamines under microwave irradiation
    Kurteva, VB
    Afonso, CAM
    GREEN CHEMISTRY, 2004, 6 (03) : 183 - 187
  • [2] Pyrazole Synthesis under Microwave Irradiation and Solvent-free Conditions
    Buriol, Lilian
    Frizzo, Clarissa P.
    Marzari, Mara R. B.
    Moreira, Dayse N.
    Prola, Lizie D. T.
    Zanatta, Nilo
    Bonacorso, Helio G.
    Martins, Marcos A. P.
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2010, 21 (06) : 1037 - 1044
  • [3] Synthesis of metallophthalocyanines under solvent-free conditions using microwave irradiation
    Shaabani, A
    Bahadoran, F
    Bazgir, A
    Safari, N
    IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION, 1999, 18 (02): : 104 - 107
  • [4] Solvent-free synthesis of sulfonephthaleins, sulfonefluoresceins and fluoresceins under microwave irradiation
    Cihelník, S
    Stibor, I
    Lhoták, P
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2002, 67 (12) : 1779 - 1789
  • [5] Solvent-free synthesis of substituted phenoxyacetic acids under microwave irradiation
    Nagy, G
    Filip, SV
    Surducan, E
    Surducan, V
    SYNTHETIC COMMUNICATIONS, 1997, 27 (21) : 3729 - 3736
  • [6] Synthesis of metallophthalocyanines under solvent-free conditions using microwave irradiation
    Shaabani, A
    JOURNAL OF CHEMICAL RESEARCH-S, 1998, (10): : 672 - 673
  • [7] Rapid solvent-free synthesis of aromatic hydrazides under microwave irradiation
    Jain, Asheesh K.
    Gupta, Pradeep K.
    Ganesan, K.
    Pande, Ambuja
    Malhotra, R. C.
    DEFENCE SCIENCE JOURNAL, 2007, 57 (02) : 267 - 270
  • [8] Solvent-Free Synthesis of Substituted Phenoxyacetic Acids under Microwave Irradiation
    Nagy, G.
    Filip, S. V.
    Surducan, E.
    Surducan, V.
    Synthetic Communications, 27 (21):
  • [9] The synthesis of α-hydroxyphosphonates mediated by microwave irradiation under solvent-free conditions
    Kaboudin, B
    Nazari, R
    JOURNAL OF CHEMICAL RESEARCH, 2002, (06) : 291 - 292
  • [10] Efficient Microwave Solvent-Free Synthesis of Flavones, Chromones, Coumarins and Dihydrocoumarins
    Bennardi, Daniel O.
    Ruiz, Diego M.
    Romanelli, Gustavo P.
    Baronetti, Graciela T.
    Thomas, Horacio J.
    Autino, Juan C.
    LETTERS IN ORGANIC CHEMISTRY, 2008, 5 (08) : 607 - 615
12345