Gastroesophageal Reflux Disease and Sudden Infant Death: Mechanisms Behind an Under-Recognized Association

被引:4
作者
Al-Adnani, Mudher [1 ]
Cohen, Marta C. [1 ]
Scheimberg, Irene [2 ]
机构
[1] Sheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, England
[2] Royal London Hosp, Dept Histopathol, London E1 1BB, England
关键词
gastroesophageal reflux; sudden infant death; GASTRIC CONTENTS; ASPIRATION; POSITION;
D O I
10.2350/09-11-0748-CR.1
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
We present 4 cases of sudden infant death in which we believe that gastroesophageal reflux (GOR) was a contributory, if not a causative, factor. Two of our patients had documented GOR reflux disease during life, and all 4 cases showed histologic evidence of GOR. No other cause of death was identified in any of the patients. Gastroesophageal reflux can cause sudden death in a vulnerable infant during a critical period of development through failure of "autoresuscitation" mechanisms.
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页码:53 / 56
页数:4
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