Gastroesophageal Reflux Disease and Sudden Infant Death: Mechanisms Behind an Under-Recognized Association
被引:4
作者:
Al-Adnani, Mudher
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Sheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, EnglandSheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, England
Al-Adnani, Mudher
[1
]
Cohen, Marta C.
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Sheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, EnglandSheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, England
Cohen, Marta C.
[1
]
Scheimberg, Irene
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Royal London Hosp, Dept Histopathol, London E1 1BB, EnglandSheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, England
Scheimberg, Irene
[2
]
机构:
[1] Sheffield Childrens Hosp NHS Fdn Trust, Dept Histopathol, Sheffield S10 2TH, S Yorkshire, England
[2] Royal London Hosp, Dept Histopathol, London E1 1BB, England
We present 4 cases of sudden infant death in which we believe that gastroesophageal reflux (GOR) was a contributory, if not a causative, factor. Two of our patients had documented GOR reflux disease during life, and all 4 cases showed histologic evidence of GOR. No other cause of death was identified in any of the patients. Gastroesophageal reflux can cause sudden death in a vulnerable infant during a critical period of development through failure of "autoresuscitation" mechanisms.