Pituitary apoplexy after cardiac surgery in a patient with subclinical pituitary adenoma: case report with review of literature

被引:0
作者
Yakupoglu, Hakan [1 ]
Onal, Mehmet Bulent [1 ]
Civelek, Erdinc [1 ]
Kircelli, Atilla [2 ]
Celasun, Bulent [3 ]
机构
[1] Med Int Hosp, Dept Neurosurg, Ankara, Turkey
[2] Gulhane Mil Acad, Dept Neurosurg, Ankara, Turkey
[3] Med Int Hosp, Dept Pathol, Ankara, Turkey
关键词
pituitary apoplexy; Sheehan's syndrome; cardiac surgery; pituitary adenoma; BYPASS-SURGERY; NERVE PALSY;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Pituitary adenoma infarction associated with cardiac surgery occurs rarely but it is a serious, life-threatening acute clinical event. Several mechanisms have been proposed but no direct cause has been clearly identified. We report a case of pituitary apoplexy occurring in a 74-year-old patient 6 hours after cardiac surgery The patient presented with confusion, unilateral ptosis and ophthalmoplegia. Neurological examination revealed right oculomotor nerve palsy and decreased level of consciousness. Magnetic resonance imaging showed a hemorrhagic and necrotic pituitary macroadenoma. After prompt endocrinological replacement therapy with hydrocortisone and levothyroxine, the confusion of the patient resolved. Removal of a non-functional macroadenoma with large necrotic areas resulted in full recovery The physician should be aware of pituitary adenoma infarction after open cardiac surgery and should remember that it can be fatal or cause permanent neurological or endocrine damage without proper treatment. Surgical and endocrine treatment can be life-saving procedures.
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页码:520 / 525
页数:6
相关论文
共 22 条
[11]  
Morokuma H, 2008, Kyobu Geka, V61, P849
[12]   Clinical features and immunohistochemical changes of pituitary apoplexy [J].
Mou, Chengzhi ;
Han, Tao ;
Zhao, Hao ;
Wang, Shaoguang ;
Qu, Yuanming .
JOURNAL OF CLINICAL NEUROSCIENCE, 2009, 16 (01) :64-68
[13]   Pituitary apoplexy: evaluation, management, and prognosis [J].
Murad-Kejbou, Sally ;
Eggenberger, Eric .
CURRENT OPINION IN OPHTHALMOLOGY, 2009, 20 (06) :456-461
[14]  
Nawar Rita N, 2008, J Intensive Care Med, V23, P75, DOI 10.1177/0885066607312992
[15]  
PLIAM MB, 1995, J CARDIAC SURG, V10, P125
[16]   PITUITARY APOPLEXY ASSOCIATED WITH CARDIAC-SURGERY [J].
SLAVIN, ML ;
BUDABIN, M .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1984, 98 (03) :291-296
[17]   Coronary bypass surgery in patients with Sheehan's syndrome [J].
Syed, AU ;
Al Fagih, MR ;
Fouda, M .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2001, 20 (06) :1264-1266
[18]   Pituitary apoplexy causing isolated blindness after cardiac bypass surgery [J].
Thurtell, Matthew J. ;
Besser, Michael ;
Halmagyi, G. Michael .
ARCHIVES OF OPHTHALMOLOGY, 2008, 126 (04) :576-578
[19]   Sheehan syndrome: A splinter of the mind [J].
Vaphiades, MS ;
Simmons, D ;
Archer, RL ;
Stringer, W .
SURVEY OF OPHTHALMOLOGY, 2003, 48 (02) :230-233
[20]   Sudden death from pituitary apoplexy in a patient presenting with an isolated sixth cranial nerve palsy [J].
Warwar, RE ;
Bhullar, SS ;
Pelstring, RJ ;
Fadell, RJ .
JOURNAL OF NEURO-OPHTHALMOLOGY, 2006, 26 (02) :95-97