Application of electroosmotic micropumps to a microfluidic system combined with a light-addressable potentiometric sensor

被引：9

作者：

Li, Xueliang ^{[1
,2
]}

Liu, Shibin ^{[1
]}

Liang, Jintao ^{[3
]}

Miyamoto, Ko-ichiro ^{[4
]}

Yoshinobu, Tatsuo ^{[2
,4
]}

机构：

[1] Northwestern Polytech Univ, Sch Elect & Informat, Xian 710072, Peoples R China

[2] Tohoku Univ, Dept Biomed Engn, Aoba Ku, 6-6-05 Aza Aoba, Sendai, Miyagi 9808579, Japan

[3] Guilin Univ Elect Technol, Sch Life & Environm Sci, Guilin 541004, Peoples R China

[4] Tohoku Univ, Dept Elect Engn, Aoba Ku, 6-6-05 Aza Aoba, Sendai, Miyagi 9808579, Japan

来源：

PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE | 2016年 / 213卷 / 06期

关键词：

droplets; electroosmotic micropumps; light-addressable potentiometric sensors; CHEMICAL IMAGING SENSOR; CELLULAR-METABOLISM; FLOW PUMP; CHANNEL; MEMBRANES; LAPS;

D O I：

10.1002/pssa.201532879

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

An on-chip electroosmotic (EO) micropump (EOP) was embedded in a microchannel combined with a light-addressable potentiometric sensor (LAPS). The flow direction and the flow rate of EO flows on the LAPS chip could be controlled by the polarity and the magnitude of the applied DC voltage. The EOP could be used as an actuator to generate a sample droplet of about 1 nL and to drive it to the sensing position of a LAPS. A design of a microfluidic system as a (bio-) chemical analysis device for measuring a small volume of sample is proposed. (C) 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1500 / 1504

页数：5

共 25 条

[1] A low-voltage nano-porous electroosmotic pump [J].

Ai, Ye ;

Yalcin, Sinan E. ;

Gu, Diefeng ;

Baysal, Oktay ;

Baumgart, Helmut ;

Qian, Shizhi ;

Beskok, Ali .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2010, 350 (02) :465-470

[2] Electroosmotic flow in poly(dimethylsiloxane) microchannels [J].

Bao, N ;

Xu, JJ ;

Zhang, Q ;

Hang, JL ;

Chen, HY .

JOURNAL OF CHROMATOGRAPHY A, 2005, 1099 (1-2) :203-206

[3] MICROMACHINED MULTICHANNEL SYSTEMS FOR THE MEASUREMENT OF CELLULAR-METABOLISM [J].

BOUSSE, L ;

MCREYNOLDS, RJ ;

KIRK, G ;

DAWES, T ;

LAM, P ;

BEMISS, WR ;

FARCE, JW .

SENSORS AND ACTUATORS B-CHEMICAL, 1994, 20 (2-3) :145-150

[4]

Bousse L. J., 1990, 4 SOL STAT SENS ACT, P173

[5] A handy liquid metal based electroosmotic flow pump [J].

Gao, Meng ;

Gui, Lin .

LAB ON A CHIP, 2014, 14 (11) :1866-1872

[6] LIGHT-ADDRESSABLE POTENTIOMETRIC SENSOR FOR BIOCHEMICAL SYSTEMS [J].

HAFEMAN, DG ;

PARCE, JW ;

MCCONNELL, HM .

SCIENCE, 1988, 240 (4856) :1182-1185

[7] A novel microphysiometer based on high sensitivity LAPS and microfluidic system for cellular metabolism study and rapid drug screening [J].

Hu, Ning ;

Wu, Chengxiong ;

Ha, Da ;

Wang, Tianxing ;

Liu, Qingjun ;

Wang, Ping .

BIOSENSORS & BIOELECTRONICS, 2013, 40 (01) :167-173

[8] Graphene oxide modified light addressable potentiometric sensor and its application for ssDNA monitoring [J].

Jia, Yunfang ;

Yin, Xue-Bo ;

Zhang, Jia ;

Zhou, Shuang ;

Song, Meng ;

Xing, Ke-Li .

ANALYST, 2012, 137 (24) :5866-5873

[9] Microchip Electrophoresis of Oligosaccharides Using Large-Volume Sample Stacking with an Electroosmotic Flow Pump in a Single Channel [J].

Kawai, Takayuki ;

Sueyoshi, Kenji ;

Kitagawa, Fumihiko ;

Otsuka, Koji .

ANALYTICAL CHEMISTRY, 2010, 82 (15) :6504-6511

[10] High-flowrate, compact electroosmotic pumps with porous polymer track-etch membranes [J].

Kwon, Kilsung ;

Park, Chul-Woo ;

Kim, Daejoong .

SENSORS AND ACTUATORS A-PHYSICAL, 2012, 175 :108-115

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