Synthesis of novel vitamin C phosphodiesters: Stability and antioxidant activity

被引：13

作者：

Morisaki, K

Ozaki, S

机构：

[1] Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama

来源：

CARBOHYDRATE RESEARCH | 1996年 / 286卷

关键词：

vitamin C derivatives; antioxidants; ascorbic acid phosphodiesters;

D O I：

10.1016/0008-6215(96)00043-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel series of hybrid L-ascorbic acid (vitamin C) phophodiesters linked at the C-2 hydroxyl group with other biologically active substances, namely myo-inositol, arbutin, 4-hydroxy-L-proline. and glycolic acid were synthesized, and their thermal stability and reducing activity against free radicals were estimated in vitro. All of the phosphodiesters exhibited high thermal stabilities: however, their antioxidant activities in vitro were generally lower than that of vitamin C. (C) 1996 Elsevier Science Ltd.

引用

页码：123 / 138

页数：16

共 54 条

[1]

Akiu S., 1988, P JPN SOC DERMATOL, V12, P138

[2] OXIDANTS, ANTIOXIDANTS, AND THE DEGENERATIVE DISEASES OF AGING [J].