Candidatus Neoehrlichia mikurensis infection identified in 2 hematooncologic patients: benefit of molecular techniques for rare pathogen detection

被引:56
作者
Pekova, Sona [1 ]
Vydra, Jan [2 ]
Kabickova, Hana [3 ]
Frankova, Sona [4 ]
Haugvicova, Renata [1 ]
Mazal, Oldrich [1 ]
Cmejla, Radek [1 ]
Hardekopf, David W. [1 ]
Jancuskova, Tereza [1 ]
Kozak, Tomas [2 ]
机构
[1] CHAMBON Labs, Lab Mol Diagnost, Prague, Czech Republic
[2] Teaching Hosp Kralovske Vinohrady, Dept Clin Hematol, Prague, Czech Republic
[3] Cent Mil Hlth Inst, Prague, Czech Republic
[4] Inst Clin & Expt Med, Dept Hepatogastroenterol, Prague, Czech Republic
关键词
Candidatus Neoerhlichia mikurensis; Lymphoma; Molecular detection of pathogens; HEMATOPOIETIC-CELL TRANSPLANTATION; PREVENTION; RODENTS; TICKS; PCR;
D O I
10.1016/j.diagmicrobio.2010.10.004
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Hematooncologic patients often host rare or fastidious pathogens. Using 16S rDNA sequencing and transmission electron microscopy, we have identified 2 lymphoma patients infected with Candidatus Neoehrlichia mikurensis. In both individuals, the clinical presentation suggested ehrlichiosis-like syndrome. We believe that molecular techniques open new vistas in the field of pathogen detection. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:266 / 270
页数:5
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