A simple, cost-effective screening protocol to rule out periprosthetic infection

被引:76
作者
Austin, Matthew S. [1 ]
Ghanem, Elie [1 ]
Joshi, Ashish [1 ]
Lindsay, Adam [1 ]
Parvizi, Javad [1 ]
机构
[1] Thomas Jefferson Univ Hosp, Dept Orthopaed Surg, Rothman Inst, Philadelphia, PA 19107 USA
关键词
periprosthetic infection; total knee arthroplasty; erythrocyte sedimentation rate; C-reactive protein;
D O I
10.1016/j.arth.2007.09.005
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The differential diagnosis of pain after total knee arthroplasty includes infection. Effective screening tools should have high sensitivity and are cost-effective. We evaluated 296 patients who underwent total knee revision at our institution. One hundred sixteen patients (39%) were classified as infected and 180 patients (61%) were considered noninfected. The mean erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) of the infected patients were 85 mm/h and 110 mg/L, respectively. The mean ESR and CRP of the noninfected patients were 22 mm/h and 7 mg/L, respectively. Five patients (4%) in the infected group had both normal ESR and CRP. Infection was suspected in all 5 patients, and an organism was cultured in 4 of the 5 cases. Erythrocyte sedimentation rate and CRP, when used in combination, serve as a useful screening tool in patients with a painful total knee arthroplasty.
引用
收藏
页码:65 / 68
页数:4
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