Alternative polyadenylation-associated loci interpret human traits and diseases

被引：4

作者：

Fang, Zhixiao ^{[1
]}

Li, Shengli ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Inst Clin Res, Sch Med, Precis Res Ctr Refractory Dis,Shanghai Gen Hosp, Shanghai 201620, Peoples R China

来源：

TRENDS IN GENETICS | 2021年 / 37卷 / 09期

关键词：

D O I：

10.1016/j.tig.2021.06.002

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Alternative polyadenylation (APA)associated genetic variants have been proposed to impact diverse human phenotypes and disorders. In a recent study, Li et al. established a landscape of 3'-untranslated region (UTR) APA quantitative trait loci (3'aQTLs) across multiple human tissues, revealing substantial 3'aQTLs that contribute to complex human traits and diseases.

引用

页码：773 / 775

页数：3

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