Elimination of different leukaemia subtypes using novel CD89-specific human cytolytic fusion proteins

被引:4
作者
Gresch, Gerrit [1 ,2 ]
Schenke, Lea [1 ,2 ]
Mladenov, Radoslav [1 ]
Zwirner, Stefan [1 ]
Cremer, Christian [2 ]
Niesen, Judith [1 ]
Grieger, Elena [1 ,2 ]
Bruemmendorf, Tim [3 ]
Jost, Edgar [3 ]
Fischer, Rainer [1 ]
Stockmeyer, Bernhard [4 ]
Barth, Stefan [1 ,2 ,5 ]
Nachreiner, Thomas [2 ]
Stein, Christoph [1 ,2 ]
机构
[1] Fraunhofer Inst Mol Biol & Appl Ecol IME, Dept Immunotherapy, Aachen, Germany
[2] RWTH Aachen Univ Hosp, Inst Appl Med Engn, Aachen, Germany
[3] RWTH Aachen Univ Hosp, Dept Haematol & Oncol Internal Med 4, Aachen, Germany
[4] Univ Erlangen Nurnberg, Dept Internal Med 5, Haematol Oncol, Erlangen, Germany
[5] Univ Cape Town, South African Res Chair Canc Biotechnol, Inst Infect Dis & Mol Med IDM, Dept Integrat Biomed Sci,Fac Hlth Sci, Cape Town, South Africa
关键词
leukaemia; human cytolytic fusion proteins (hCFP); angiogenin (Ang); microtubule-associated protein tau (MapTau); single-chain Fragment variable (scFv); FC-ALPHA-RI; IMMUNOTOXIN RESISTANCE; CANCER; METHYLATION; GENERATION; ANGIOGENIN; RECEPTOR; PROMOTER; THERAPY;
D O I
10.1111/bjh.14971
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:313 / 317
页数:5
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