NR4A nuclear orphan receptors: protective in vascular disease?

被引：61
作者：
Pols, Thijs W. H. [1 ]
Bonta, Peter I. [1 ]
de Vries, Carlie J. M. [1 ]
机构：
[1] Univ Amsterdam, Acad Med Ctr, Dept Med Biochem, NL-1105 AZ Amsterdam, Netherlands
来源：
CURRENT OPINION IN LIPIDOLOGY | 2007年 / 18卷 / 05期
关键词：
atherosclerosis; inflammation; metabolism; NR4A nuclear receptors; restenosis;
D O I：
10.1097/MOL.0b013e3282ef77d1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The involvement of NR4A nuclear receptors in both metabolism and in processes in the vessel wall supports a substantial role for NR4A nuclear receptors in the development of vascular disease.
引用
收藏
页码：515 / 520
页数：6
相关论文
共 46 条
[1]   TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest [J].
Arkenbout, EK ;
van Bragt, M ;
Eldering, E ;
van Bree, C ;
Grimbergen, JM ;
Quax, PHA ;
Pannekoek, H ;
de Vries, CJM .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (09) :1535-1540
[2]   Protective function of transcription factor TR3 orphan receptor in atherogenesis - Decreased lesion formation in carotid artery ligation model in TR3 transgenic mice [J].
Arkenbout, EK ;
de Waard, V ;
van Bragt, M ;
van Achterberg, TAE ;
Grimbergen, JM ;
Pichon, B ;
Pannekoek, H ;
de Vries, CJM .
CIRCULATION, 2002, 106 (12) :1530-1535
[3]  
Auwerx J, 1999, CELL, V97, P161
[4]   A nuclear receptor atlas: Macrophage activation [J].
Barish, GD ;
Downes, M ;
Alaynick, WA ;
Yu, RT ;
Ocampo, CB ;
Bookout, AL ;
Mangelsdorf, DJ ;
Evans, RM .
MOLECULAR ENDOCRINOLOGY, 2005, 19 (10) :2466-2477
[5]   NR4A nuclear receptors in atherosclerosis and vein-graft disease [J].
Bonta, Peter I. ;
Pols, Thijs W. H. ;
de Vries, Carlie J. M. .
TRENDS IN CARDIOVASCULAR MEDICINE, 2007, 17 (03) :105-111
[6]   Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses [J].
Bonta, Peter I. ;
van Tiel, Claudia M. ;
Vos, Mariska ;
Pols, Thijs W. H. ;
van Thienen, Johannes V. ;
Ferreira, Valerie ;
Arkenbout, E. Karin ;
Seppen, Jurgen ;
Spek, C. Arnold ;
van der Poll, Tom ;
Pannekoek, Hans ;
de Vries, Carlie J. M. .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (10) :2288-2294
[7]   Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network [J].
Bookout, Angie L. ;
Jeong, Yangsik ;
Downes, Michael ;
Yu, Ruth T. ;
Evans, Ronald M. ;
Mangelsdorf, David J. .
CELL, 2006, 126 (04) :789-799
[8]  
Cara CJ, 2004, MED SCI MONITOR, V10, pRA247
[9]   TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells [J].
de Waard, Vivian ;
Arkenbout, E. Karin ;
Vos, Mariska ;
Mocking, Astrid I. M. ;
Niessen, Hans W. M. ;
Stooker, Wilm ;
de Moo, Bas A. J. M. ;
Quax, Paul H. A. ;
Bakker, Erik N. T. P. ;
VanBavel, Ed ;
Pannekoek, Hans ;
de Vries, Carlie J. M. .
AMERICAN JOURNAL OF PATHOLOGY, 2006, 168 (06) :2027-2035
[10]   Identification of novel mediators of NF-κB through genome-wide survey of monocyte adherence-induced genes [J].
Diatchenko, L ;
Romanov, S ;
Malinina, I ;
Clarke, J ;
Tchivilev, I ;
Li, XL ;
Makarov, SS .
JOURNAL OF LEUKOCYTE BIOLOGY, 2005, 78 (06) :1366-1377
12345