Ethanol Sensitizes the Nervous System of Caenorhabditis elegans Nematode to Heat Stress

被引：1
作者：
Gainutdinov, M. Kh. [1 ]
Timoshenko, A. Kh. [1 ]
Petrov, A. M. [1 ]
Gainutdinov, T. M. [1 ]
Kalinnikova, T. B. [1 ]
机构：
[1] Acad Sci Tatarstan, Inst Ecol Nat Syst, Kazan, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2010年 / 150卷 / 01期
关键词：
ethanol; C; elegans; heat stress; adaptation; RECEPTORS; ALCOHOL; DEATHS;
D O I：
10.1007/s10517-010-1067-0
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Ethanol sensitizes the nervous system of C. elegans to heat stress, which manifested in exacerbation of locomotion disturbances induced by exposure to constant temperature 36 degrees C. Adaptation of C. elegans to high temperature by heat shock (1 h at 32 degrees C and 1 h at 18 degrees C) or two-hour exposure at 30 degrees C resulted considerably reduced sensitivity of the nervous system to the negative effects of ethanol under conditions of heat stress.
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页码：55 / 57
页数：3
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