Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation

被引：442

作者：

Yashima, E ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Engn, Dept Mol Design & Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

JOURNAL OF CHROMATOGRAPHY A | 2001年 / 906卷 / 1-2期

关键词：

reviews; chiral stationary phases; LC; enantiomer separation; polysaccharides;

D O I：

10.1016/S0021-9673(00)00501-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent developments of polysaccharide-based chiral stationary phases (CSPs) for the direct separation of enantiomers in high-performance liquid chromatography (HPLC) are mainly reviewed together with the results on mechanistic studies by means of chromatography, NMR and mass spectroscopies, and computational methods. Miscellaneous applications of polysaccharide derivatives to the newly developed, chiral dynamic high-performance liquid chromatography (DHPLC) for obtaining a nonracemic compound are also described. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：105 / 125

页数：21

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