Synthesis and Insecticidal Activities of Novel Anthranilic Diamides Containing Modified N-Pyridylpyrazoles

被引：96

作者：

Feng, Qi ^{[1
]}

Liu, Zhi-Li ^{[1
]}

Xiong, Li-Xia ^{[1
]}

Wang, Ming-Zhong ^{[1
]}

Li, Yong-Qiang ^{[1
]}

Li, Zheng-Ming ^{[1
]}

机构：

[1] Nankai Univ, Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2010年 / 58卷 / 23期

基金：

中国国家自然科学基金;

关键词：

Anthranilic diamides; N-pyridylpyrazole; Insecticidal activity; POTENT; DESIGN;

D O I：

10.1021/jf102842r

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

In order to look for novel insecticides targeting the ryanodine receptor, four new series of anthranilic diamides containing modified N-pyridylpyrazoles were designed and synthesized. All of the compounds were characterized and confirmed by H-1 NMR, C-13 NMR, and HRMS. The single crystal structure of 10c was determined by X-ray diffraction. Their insecticidal activities against oriental armyworm (Mythimna separata) and diamondback moth (Plutefia xylostella) indicated that most of the compounds showed moderate to high activities at the tested concentration, while compound 19 showed comparable higher activity at the concentration of 0.125 mg/L. The preliminary structure-activity relationship (SAR) was discussed.

引用

页码：12327 / 12336

页数：10

共 28 条

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