Seroprevalence of Toxoplasma gondii antibodies in North Indian blood donors: Implications for transfusion transmissible toxoplasmosis

被引：31

作者：

Elhence, Priti ^{[1
]}

Agarwal, Prashant ^{[1
]}

Prasad, Kashi Nath ^{[2
]}

Chaudhary, Rajendra K. ^{[1
]}

机构：

[1] Sanjay Gandhi Post Grad Inst Med Sci, Dept Transfus Med, Lucknow 226014, Uttar Pradesh, India

[2] Sanjay Gandhi Post Grad Inst Med Sci, Dept Microbiol, Lucknow 226014, Uttar Pradesh, India

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2010年 / 43卷 / 01期

关键词：

Toxoplasina gondii; Blood donors; Seroprevalence; TRANSPLANT RECIPIENTS; PREVALENCE;

D O I：

10.1016/j.transci.2010.05.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Transfusion transmitted Toxoplasma gondii (T. gondii) can result in significant clinical consequences in immunocompromised and multiply transfused patients, pregnant women and fetus etc. Anti-T gondii seroprevalence, specifically IgM antibodies reflect the risk of transfusion transmission. Methods: Four hundred and ninety-three blood donors in a tertiary care hospital in North India were screened for IgG and IgM anti-T. gondii antibodies by enzyme linked immunosorbent assay (ELISA). Results: The prevalence of IgG and IgM anti-T. gondii antibodies was 51.8% and 5% respectively. The prevalence was higher in females (M = 51.6%, F = 89.2%) and in replacement donors (replacement donors = 63.2%, voluntary donors = 33.5%). Conclusion: The donor population constitutes a significant risk of transfusion transmitted toxoplasmosis. Effective strategies are required to prevent transfusion transmitted toxoplasmosis. (c) 2010 Elsevier Ltd. All rights reserved.

引用

页码：37 / 40

页数：4

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