Ep-CAM overexpression in breast cancer as a predictor of survival

被引：246

作者：

Gastl, G ^{[1
]}

Spizzo, G

Obrist, P

Dünser, M

Mikuz, G

机构：

[1] Univ Innsbruck, Div Haematol & Oncol, A-6020 Innsbruck, Austria

[2] Univ Innsbruck, Inst Pathol, A-6020 Innsbruck, Austria

[3] Univ Innsbruck, Dept Surg, A-6020 Innsbruck, Austria

来源：

LANCET | 2000年 / 356卷 / 9246期

关键词：

D O I：

10.1016/S0140-6736(00)03312-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.

引用

页码：1981 / 1982

页数：2

共 5 条

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