Synthesis and characterization of an alendronate-chitosan conjugate

被引：5

作者：

Shao, Xiaohong ^{[1
]}

Xu, Jiqing ^{[1
]}

Jiao, Yanpeng ^{[1
]}

Zhou, Changren ^{[1
]}

机构：

[1] Jinan Univ, Dept Mat Sci & Engn, Guangzhou 510630, Guangdong, Peoples R China

来源：

MEDICAL MATERIALS AND ENGINEERING | 2012年 / 140卷

关键词：

chitosan; alendronate; polymer-drug conjugates;

D O I：

10.4028/www.scientific.net/AMM.140.53

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The biomineral-binding alendronate-chitosan conjugate (Scheme 1) was developed as a novel drug delivery system. Alendronate was conjugated to the hydroxyl groups of chitosan, thereby maintaining the amino groups of chitosan intact. By means of FT-IR and H-1 NMR, the characterization was conducted to confirm the successful synthesis of alendronate-chitosan conjugate,

引用

页码：53 / 57

页数：5

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