Performance analysis of solid-state nanopore chemical sensor

被引：26
作者：
Tang, Yongliang [1 ]
Cao, Liuxuan [2 ]
Zhan, Kan [3 ]
Xie, Yu [1 ]
Sun, Daoheng [1 ]
Hou, Xu [3 ,4 ,5 ]
Chen, Songyue [1 ]
机构：
[1] Xiamen Univ, Sch Aerosp Engn, Xiamen 361005, Peoples R China
[2] Xiamen Univ, Coll Energy, Xiamen 361005, Peoples R China
[3] Xiamen Univ, Coll Chem & Chem Engn, Collaborat Innovat Ctr Chem Energy Mat, Xiamen 361005, Peoples R China
[4] Xiamen Univ, Coll Phys Sci & Technol, Xiamen 361005, Peoples R China
[5] Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2019年 / 286卷
基金：
国家重点研发计划; 中国国家自然科学基金;
关键词：
Nanopore; Sensitivity; Limit of detection; Noise; Chemical sensor; SURFACE-CHARGE; ION-TRANSPORT; DNA; IDENTIFICATION; NOISE;
D O I：
10.1016/j.snb.2019.01.129
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The performance of solid-state nanopore chemical sensor is analyzed in this paper with respect to sensitivity and detection limit. A simplified analytical model is derived to provide better understanding on the conductivity change of nanopores with respect to the radius, ionic concentration, and surface charge density. The paper shows that the sensitivity and limit of detection can be optimized by working in a background solution of low ionic concentration solution (in the range of mM) and high mobility cation, with an appropriate high input voltage. The current noise is analyzed in the form of current power spectra density, which act as a solid support for understanding the noise behavior and detection resolution analysis.
引用
收藏
页码：315 / 320
页数：6
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