Catalyst-free benzylic C(sp3)-H cross-coupling with organotrifluoroborates enabled by electrochemistry

被引：14
|
作者：
Li, Chao [1 ]
Ding, Ran [1 ,3 ]
Guo, Heng-Yi [2 ]
Xia, Shuang [2 ]
Shu, Lei [1 ]
Wang, Pei-Long [1 ,2 ]
Li, Hongji [1 ]
机构：
[1] Huaibei Normal Univ, Sch Chem & Mat Sci, Key Lab Green & Precise Synthet Chem & Applicat, Minist Educ, Huaibei 235000, Anhui, Peoples R China
[2] Huaibei Normal Univ, Informat Coll, Huaibei 235000, Peoples R China
[3] Anhui Sci & Technol Univ, Coll Chem & Mat Engn, Bengbu 233100, Anhui, Peoples R China
来源：
GREEN CHEMISTRY | 2022年 / 24卷 / 20期
基金：
美国国家科学基金会;
关键词：
C-H BONDS; AMINATION; FUNCTIONALIZATION; ALKYLATION; ACTIVATION; XANTHENES; OXIDATION; ETHERS; SALTS; ACIDS;
D O I：
10.1039/d2gc02204d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we report a rare catalyst-free electrochemical cross-coupling of benzylic C-H bonds with organotrifluoroborates, which readily proceeds at room temperature and provides a unique protocol for forging C(sp(3))-C(sp(3)), C(sp(3))-C(sp(2)) and C(sp(3))-C(sp) bonds. In particular, this work discloses the dual role of organotrifluoroborates serving both as a coupling partner and an electrolyte in C(sp(3))-H functionalization.
引用
收藏
页码：7883 / 7888
页数：6
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