Bio-inspired special wettability in oral antibacterial applications

被引:5
作者
Zhang, Xin [1 ,2 ,3 ]
Bai, Rushui [1 ,2 ,3 ]
Sun, Qiannan [1 ,2 ,3 ]
Zhuang, Zimeng [1 ,2 ,3 ]
Zhang, Yunfan [1 ,2 ,3 ]
Chen, Si [1 ,2 ,3 ]
Han, Bing [1 ,2 ,3 ]
机构
[1] Peking Univ, Sch & Hosp Stomatol, Dept Orthodont, Beijing, Peoples R China
[2] Natl Engn Lab Digital & Mat Technol Stomatol, Beijing, Peoples R China
[3] Beijing Key Lab Digital Stomatol, Beijing, Peoples R China
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
bio-inspired; super wettability; low-fouling surfaces; antibacterial; oral biofilm management; SELF-ASSEMBLED MONOLAYERS; POLY(ETHYLENE GLYCOL); STREPTOCOCCUS-MUTANS; POLYETHYLENE-GLYCOL; PROTEIN ADSORPTION; BACTERIAL ADHESION; IN-VITRO; HYDROXYAPATITE SURFACE; PHOSPHOLIPID POLYMERS; BIOFILM FORMATION;
D O I
10.3389/fbioe.2022.1001616
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Most oral diseases originate from biofilms whose formation is originated from the adhesion of salivary proteins and pioneer bacteria. Therefore, antimicrobial materials are mainly based on bactericidal methods, most of which have drug resistance and toxicity. Natural antifouling surfaces inspire new antibacterial strategies. The super wettable surfaces of lotus leaves and fish scales prompt design of biomimetic oral materials covered or mixed with super wettable materials to prevent adhesion. Bioinspired slippery surfaces come from pitcher plants, whose porous surfaces are infiltrated with lubricating liquid to form superhydrophobic surfaces to reduce the contact with liquids. It is believed that these new methods could provide promising directions for oral antimicrobial practice, improving antimicrobial efficacy.
引用
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页数:13
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