G-CSF producing oral carcinoma with diffuse uptake of FDG in the bone marrow: A case report

被引：11

作者：

Kuroshima, Takeshi ^{[1
]}

Wada, Mayumi ^{[2
]}

Sato, Takehiko ^{[2
]}

Takano, Masashi ^{[2
]}

Makino, Shujiroh ^{[2
]}

机构：

[1] Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Div Oral Hlth Sci, Dept Oral Restitut,Oral & Maxillofacial Surg, Tokyo 1138549, Japan

[2] Hokuto Hosp, Dept Oral Surg, Obihiro, Hokkaido 0800833, Japan

来源：

ONCOLOGY LETTERS | 2018年 / 15卷 / 01期

关键词：

G-CSF producing tumor; oral cancer; FDG-PET; bone marrow; COLONY-STIMULATING FACTOR; HORMONE-RELATED PROTEIN; ANAPLASTIC CARCINOMA; CANCER;

D O I：

10.3892/ol.2017.7422

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 78-year-old male patient was referred to the Department of Oral Surgery, Hokuto Hospital (Obihiro, Japan) for painless swelling on the left neck and tongue. Histopathological examination of a biopsy specimen resulted in a diagnosis of squamous cell carcinoma of the tongue. Imaging examinations revealed cervical lymph node metastases on both sides, along with diffuse uptake of F-18-fluorodeoxyglucose (FDG) in the bone marrow of the spine and pelvis. Hematologic tests revealed an increased white blood cell (WBC) count and serum concentrations of granulocyte colony stimulating factor (G-CSF). These findings suggested a G-CSF producing tumor, with fluctuations of WBC count, serum G-CSF concentration, and FDG uptake in the bone marrow, associated with tumor shrinkage and enlargement, an indicator of tumor status.

引用

页码：1241 / 1245

页数：5

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