Anti-inflammatory and cytotoxic components from Dichrocephala integrifolia

被引：7

作者：

Lee, Chia-Lin ^{[1
,2
]}

Yen, Ming-Hon ^{[3
]}

Hwang, Tsong-Long ^{[4
,5
,6
,7
]}

Yang, Juan-Cheng ^{[2
,8
]}

Peng, Chieh-Yu ^{[2
,8
]}

Chen, Chao-Jung ^{[9
,10
]}

Chang, Wen-Yi ^{[4
,5
,6
,7
]}

Wu, Yang-Chang ^{[2
,8
,11
,12
]}

机构：

[1] China Med Univ, Dept Cosmeceut, Taichung 40402, Taiwan

[2] China Med Univ Hosp, Chinese Med Res & Dev Ctr, Taichung 40447, Taiwan

[3] Kaohsiung Med Univ, Sch Pharm, Kaohsiung 80708, Taiwan

[4] Chang Gung Univ, Coll Med, Healthy Aging Res Ctr, Sch Tradit Med,Grad Inst Nat Prod, Taoyuan 33302, Taiwan

[5] Chang Gung Univ, Healthy Aging Res Ctr, Chinese Herbal Med Res Team, Taoyuan 33302, Taiwan

[6] Chang Gung Univ Sci & Technol, Dept Cosmet Sci, Taoyuan 33302, Taiwan

[7] Chang Gung Univ Sci & Technol, Res Ctr Ind Human Ecol, Taoyuan 33302, Taiwan

[8] China Med Univ, Coll Pharm, Sch Pharm, Taichung 40402, Taiwan

[9] China Med Univ, Grad Inst Integrated Med, Taichung 40402, Taiwan

[10] China Med Univ Hosp, Dept Med Res, Prote Core Lab, Taichung 40447, Taiwan

[11] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 80708, Taiwan

[12] China Med Univ Hosp, Ctr Mol Med, Taichung 40402, Taiwan

来源：

PHYTOCHEMISTRY LETTERS | 2015年 / 12卷

关键词：

Dichrocephala integrifolia; Asteraceae; Anti-inflammatory effect; Cytotoxicity; DITERPENES; SESQUITERPENES;

D O I：

10.1016/j.phytol.2015.04.012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Portulide glucoside A (1), 14-acetoxy-9-epi-britanlin A (2), and dichroditerpene A (3) along with eight known compounds were isolated from Dichrocephala integrifolia. Diterpenoids 3 and 5 showed antineutrophilic inflammatory activities against not only superoxide anion generation with IC50 values of 1.74 and 4.40 mu M, but also elastase release with IC50 values of 1.32 and 3.67 mu M, respectively. Additionally, sinapyl alcohols 8 and 9 showed moderate cytotoxicity toward DU145 human prostate cancer cell line with IC50 values of 24.1 and 19.0 mu M, respectively. Isolates 1-10 were found for the first time in this plant. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：237 / 242

页数：6

共 50 条

[31] Phytochemicals from Carissa carandas with potent cytotoxic and anti-inflammatory activities
Bano, Zarina
Begum, Sabira
Ali, Syed Saqib
Kiran, Zareena
Siddiqui, Bina S.
Ahmed, Ayaz
Khawaja, Shariqa
Fatima, Fatima
Jabeen, Almas
NATURAL PRODUCT RESEARCH, 2022, 36 (06) : 1587 - 1592
[32] New Anti-Inflammatory Aromatic Components from Antrodia camphorata
Chen, Yu-Chang
Chiu, His-Lin
Chao, Che-Yi
Lin, Wen-Hsin
Chao, Louis Kuoping
Huang, Guan-Jhong
Kuo, Yueh-Hsiung
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (03): : 4629 - 4639
[33] Cytotoxic and Anti-Inflammatory Sesquiterpenes from the Whole Plants of Centipeda minima
Xue, Peng-Hui
Zhang, Nan
Liu, Da
Zhang, Qing-Ran
Duan, Jing-Shi
Yu, Ya-Qin
Li, Jin-Yan
Cao, Shi-Jie
Zhao, Feng
Kang, Ning
Qiu, Feng
JOURNAL OF NATURAL PRODUCTS, 2021, 84 (02): : 247 - 258
[34] New diterpenoids and cytotoxic and anti-inflammatory diterpenoids from Amentotaxus formosana
Chen, Hui-Ling
Lin, Kai-Wei
Gan, Kim-Hong
Wang, Jih-Pyang
Won, Shen-Jeu
Lin, Chun-Nan
FITOTERAPIA, 2011, 82 (02) : 219 - 224
[35] Anti-inflammatory and Cytotoxic Triterpenes from the Rot Roots of Panax notoginseng
Shang, Jia-Huan
Xu, Guo-Wei
Zhu, Hong-Tao
Wang, Dong
Yang, Chong-Ren
Zhang, Ying-Jun
NATURAL PRODUCTS AND BIOPROSPECTING, 2019, 9 (04) : 287 - 295
[36] Anti-Inflammatory and Cytotoxic Compounds Isolated from Plants of Euphorbia Genus
Rojas-Jimenez, Sarai
Valladares-Cisneros, Maria Guadalupe
Salinas-Sanchez, David Osvaldo
Perez-Ramos, Julia
Sanchez-Perez, Leonor
Perez-Gutierrez, Salud
Campos-Xolalpa, Nimsi
MOLECULES, 2024, 29 (05):
[37] Anti-inflammatory and Cytotoxic Triterpenes from the Rot Roots of Panax notoginseng
Jia-Huan Shang
Guo-Wei Xu
Hong-Tao Zhu
Dong Wang
Chong-Ren Yang
Ying-Jun Zhang
Natural Products and Bioprospecting, 2019, 9 : 287 - 295
[38] Anti-Inflammatory and Cytotoxic Potential of New Phenanthrenoids from Luzula sylvatica
Gainche, Mael
Ripoche, Isabelle
Senejoux, Francois
Cholet, Juliette
Ogeron, Clemence
Decombat, Caroline
Danton, Ombeline
Delort, Laetitia
Vareille-Delarbre, Marjolaine
Berry, Alexandre
Vermerie, Marion
Fraisse, Didier
Felgines, Catherine
Ranouille, Edwige
Berthon, Jean-Yves
Priam, Julien
Saunier, Etienne
Tourrette, Albert
Troin, Yves
Caldefie-Chezet, Florence
Chalard, Pierre
MOLECULES, 2020, 25 (10):
[39] Phenylpropanoids from Croton velutinus with cytotoxic, trypanocidal and anti-inflammatory activities
Abreu, Lucas Silva
do Nascimento, Yuri Mangueira
do Espirito-Santo, Renan Fernandes
Meira, Cassio Santana
Santos, Ivanilson Pimenta
Brandao, Railda Batista
Souto, Augusto Lopes
Silva Guedes, Maria Lenise
Pereira Soares, Milena Botelho
Villarreal, Cristiane Flora
da Silva, Marcelo Sobral
Velozo, Eudes da Silva
Tavares, Josean Fechine
FITOTERAPIA, 2020, 145
[40] Anti-inflammatory and Cytotoxic Chemical Constituents from the Trunks of Berberis wallichiana
Bui Van Thanh
Nguyen Thi Van Anh
Chu Thi Thu Ha
Dinh Thi Thu Thuy
Do Hoang Giang
Nguyen Tien Dat
BIORESOURCES, 2022, 17 (03): : 4297 - 4305

← 1 2 3 4 5 →