The usefulness of middle cerebral artery Doppler assessment in the treatment of the fetus at risk for anemia

被引:70
作者
Moise, Kenneth J., Jr. [1 ]
机构
[1] Texas Childrens Hosp, Texas Childrens Fetal Ctr, Houston, TX 77030 USA
关键词
fetal anemia; MCA; middle cerebral artery Doppler assessment; red cell alloimmunization;
D O I
10.1016/j.ajog.2007.10.788
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The use of Doppler ultrasound evaluation to measure the peak systolic velocity of the fetal middle cerebral artery (MCA) has been a major breakthrough in the noninvasive detection of fetal anemia. An elevated peak MCA velocity of > 1.5 multiples of the median is useful in the timing of the initial intrauterine transfusion (IUT) in the red cell-alloimmunized pregnancies. Data reported to date suggest that a threshold of 1.32 multiples of the median can be used to time the second IUT; the MCA Doppler evaluation does not appear sensitive for the timing of subsequent IUTs in these pregnancies. The peak MCA velocity has also proved useful in the detection of other anemic states that include Kell alloimmunization, fetal parvovirus infection, fetomaternal hemorrhage, alphathalassemia, and after-laser therapy for twin-twin transfusion.
引用
收藏
页码:161.e1 / 161.e4
页数:4
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