Stokes shift emission spectroscopy of human tissue and key biomolecules

被引:77
作者
Alfano, RR [1 ]
Yang, YL
机构
[1] CUNY City Coll, Inst Ultrafast Spect & Lasers, New York, NY 10031 USA
[2] CUNY City Coll, New York State Ctr Adv Technol Ultrafast Photon M, New York, NY 10031 USA
[3] CUNY City Coll, Dept Phys, New York, NY 10031 USA
[4] CUNY, Grad Sch, Inst Ultrafast Spect & Lasers, New York, NY 10031 USA
[5] CUNY, Grad Sch, New York State Ctr Adv Technol Ultrafast Photon M, New York, NY 10031 USA
[6] CUNY, Grad Sch, Dept Phys, New York, NY 10031 USA
关键词
diagnostic; fluorescence; optical biopsy; spectroscopy; Stokes shift (SS); tissues;
D O I
10.1109/JSTQE.2003.811285
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The Stokes-shifted emission spectra were measured for various photoactive biomolecules in aqueous solution and tissue such as tryptophan, collagen, nicotinamide adenine dinucleotide, and flavin. Information is obtained on the molecular activity in the tissue. This new approach allows for the extraction of some new information not obtained from excitation and/or fluorescence spectroscopy for a single spectral scan.
引用
收藏
页码:148 / 153
页数:6
相关论文
共 8 条
  • [1] LASER-INDUCED FLUORESCENCE SPECTROSCOPY FROM NATIVE CANCEROUS AND NORMAL TISSUE
    ALFANO, RR
    TATA, DB
    CORDERO, J
    TOMASHEFSKY, P
    LONGO, FW
    ALFANO, MA
    [J]. IEEE JOURNAL OF QUANTUM ELECTRONICS, 1984, 20 (12) : 1507 - 1511
  • [2] ULTRAFAST PHENOMENA IN LIQUIDS AND SOLIDS
    ALFANO, RR
    SHAPIRO, SL
    [J]. SCIENTIFIC AMERICAN, 1973, 228 (06) : 42 - &
  • [3] ALFANO RR, 1991, B NEW YORK ACAD MED, V67, P143
  • [4] FLUORESCENCE-SPECTRA FROM CANCEROUS AND NORMAL HUMAN-BREAST AND LUNG TISSUES
    ALFANO, RR
    TANG, GC
    PRADHAN, A
    LAM, W
    CHOY, DSJ
    OPHER, E
    [J]. IEEE JOURNAL OF QUANTUM ELECTRONICS, 1987, 23 (10) : 1806 - 1811
  • [5] Time-resolved fluorescence and photon migration studies in biomedical and model random media
    Das, BB
    Liu, F
    Alfano, RR
    [J]. REPORTS ON PROGRESS IN PHYSICS, 1997, 60 (02) : 227 - 292
  • [6] Henderson B., 1989, OPTICAL SPECTROSCOPY, p[197, 415]
  • [7] RIDLEY BK, 1982, QUANTUM PROCESSES SE, P237
  • [8] Fundamental differences of excitation spectrum between malignant and benign breast tissues
    Yang, YL
    Katz, A
    Celmer, EJ
    ZurawskaSzczepaniak, MZ
    Alfano, RR
    [J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1997, 66 (04) : 518 - 522