Year in review 2009: Critical Care - infection

被引：101

作者：

Harbarth, Stephan ^{[1
]}

Haustein, Thomas

机构：

[1] Univ Hosp Geneva, Infect Control Program, CH-1211 Geneva 14, Switzerland

来源：

CRITICAL CARE | 2010年 / 14卷 / 06期

关键词：

VENTILATOR-ASSOCIATED PNEUMONIA; COMBINATION ANTIBIOTIC-THERAPY; RESPIRATORY-TRACT INFECTIONS; NOSOCOMIAL INFECTION; PROCALCITONIN; DECONTAMINATION; CHLORHEXIDINE; UNIT; SURVEILLANCE; PERITONITIS;

D O I：

10.1186/cc9268

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

In 2009 Critical Care provided important and clinically relevant research data for management and prevention of infections in critically ill patients. The present review summarises the results of these observational studies and clinical trials and discusses them in the context of the current relevant scientific and clinical background. In particular, we discuss recent epidemiologic data on nosocomial infections in intensive care units, present new approaches to prevention of ventilator-associated pneumonia, describe recent advances in biomarker-guided antibiotic stewardship and attempt to briefly summarise specific challenges related to the management of infections caused by multidrug-resistant microorganisms and influenza A (H1N1).

引用

页数：7

共 52 条

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Hortal, Javier ;

Giannella, Maddalena ;

Jesus Perez, Maria ;

Maria Barrio, Jose ;

Desco, Manuel ;

Bouza, Emilio ;

Munoz, Patricia .

INTENSIVE CARE MEDICINE, 2009, 35 (09) :1518-1525

[22] Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe [J].

Hortal, Javier ;

Munoz, Patricia ;

Cuerpo, Gregorio ;

Litvan, Hector ;

Rosseel, Peter M. ;

Bouza, Emilio .

CRITICAL CARE, 2009, 13 (03)

[23] Estimating Attributable Mortality Due to Nosocomial Infections Acquired in Intensive Care Units [J].

Januel, Jean-Marie ;

Harbarth, Stephan ;

Allard, Robert ;

Voirin, Nicolas ;

Lepape, Alain ;

Allaouchiche, Bernard ;

Guerin, Claude ;

Lehot, Jean-Jacques ;

Robert, Marc-Olivier ;

Fournier, Gerard ;

Jacques, Didier ;

Chassard, Dominique ;

Gueugniaud, Pierre-Yves ;

Artru, Francois ;

Petit, Paul ;

Robert, Dominique ;

Mohammedi, Ismael ;

Girard, Raphaelle ;

Cetre, Jean-Charles ;

Nicolle, Marie-Christine ;

Grando, Jacqueline ;

Fabry, Jacques ;

Vanhems, Philippe .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2010, 31 (04) :388-394

[24] Methicillin-Resistant Staphylococcus aureus Decolonization: "Yes, We Can," But Will It Help? [J].

Kluytmans, Jan ;

Harbarth, Stephan .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2009, 30 (07) :633-635

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Sobel, JD ;

Ruhnke, M ;

Pappas, PG ;

Viscoli, C ;

Rex, JH ;

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Church, LWP ;

Brown, JM ;

Schlamm, HT ;

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Hilton, F ;

Hodges, MR .

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[26] Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis [J].

Kumar, Anand ;

Zarychanski, Ryan ;

Light, Bruce ;

Parrillo, Joseph ;

Maki, Dennis ;

Simon, Dave ;

Laporta, Denny ;

Lapinsky, Steve ;

Ellis, Paul ;

Mirzanejad, Yazdan ;

Martinka, Greg ;

Keenan, Sean ;

Wood, Gordon ;

Arabi, Yaseen ;

Feinstein, Daniel ;

Kumar, Aseem ;

Dodek, Peter ;

Kravetsky, Laura ;

Doucette, Steve .

CRITICAL CARE MEDICINE, 2010, 38 (09) :1773-1785

[27] Severe Community-Acquired Pneumonia: Validation of the Infectious Diseases Society of America/American Thoracic Society Guidelines to Predict an Intensive Care Unit Admission [J].

Liapikou, Adamantia ;

Ferrer, Miquel ;

Polverino, Eva ;

Balasso, Valentina ;

Esperatti, Mariano ;

Piner, Raquel ;

Mensa, Jose ;

Luque, Nestor ;

Ewig, Santiago ;

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CLINICAL INFECTIOUS DISEASES, 2009, 48 (04) :377-385

[28] Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia [J].

Luyt, Charles-Edouard ;

Clavel, Marc ;

Guntupalli, Kalpalatha ;

Johannigman, Jay ;

Kennedy, John I. ;

Wood, Christopher ;

Corkery, Kevin ;

Gribben, Dennis ;

Chastre, Jean .

CRITICAL CARE, 2009, 13 (06)

[29] Aerosolized antibiotics to treat ventilator-associated pneumonia [J].

Luyt, Charles-Edouard ;

Combes, Alain ;

Nieszkowska, Ania ;

Trouillet, Jean-Louis ;

Chastre, Jean .

CURRENT OPINION IN INFECTIOUS DISEASES, 2009, 22 (02) :154-158

[30] Determinants of mortality in non-neutropenic ICU patients with candidaemia [J].

Marriott, Deborah J. E. ;

Playford, E. Geoffrey ;

Chen, Sharon ;

Slavin, Monica ;

Nguyen, Quoc ;

Ellis, David ;

Sorrell, Tania C. .

CRITICAL CARE, 2009, 13 (04)

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