Characteristics of images of angiographically proven normal coronary arteries acquired by adenosine-stress thallium-201 myocardial perfusion SPECT/CT-IQ.SPECT with CT attenuation correction changed stepwise

被引:6
作者
Takahashi, Teruyuki [1 ,2 ]
Tanaka, Haruki [3 ]
Kozono, Nami [2 ,4 ]
Tanakamaru, Yoshiki [1 ,2 ]
Idei, Naomi [2 ,5 ]
Ohashi, Norihiko [2 ,5 ]
Ohtsubo, Hideki [2 ,5 ]
Okada, Takenori [2 ,5 ]
Yasunobu, Yuji [6 ]
Kaseda, Shunichi [2 ,5 ]
机构
[1] Hiroshima Red Cross Hosp, Dept Radiol, Hiroshima, Japan
[2] Atom Bomb Survivors Hosp, Hiroshima, Japan
[3] Miyoshi Cent Hosp, Dept Cardiol, Hiroshima 7288502, Japan
[4] Hiroshima Red Cross Hosp, Dept Med Informat Management, Hiroshima, Japan
[5] Hiroshima Red Cross Hosp, Dept Cardiol, Hiroshima, Japan
[6] Miyoshi Med Assoc Hosp, Dept Cardiol, Hiroshima, Japan
关键词
Myocardial perfusion imaging; Attenuation artifact; Computed tomography number conversion software; JOINT POSITION STATEMENT; RISK STRATIFICATION; NUCLEAR-CARDIOLOGY; DISEASE; SOCIETY; MISREGISTRATION; ASSOCIATION; ACCURACY; THERAPY;
D O I
10.1007/s12149-014-0935-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective Although several studies have shown the diagnostic and prognostic value of CT-based attenuation correction (AC) of single photon emission computed tomography (SPECT) images for diagnosing coronary artery disease (CAD), this issue remains a matter of debate. To clarify the characteristics of CT-AC SPECT images that might potentially improve diagnostic performance, we analyzed images acquired using adenosine-stress thallium-201 myocardial perfusion SPECT/CT equipped with IQ.SPECT (SPECT/CT-IQ.SPECT) from patients with angiographically proven normal coronary arteries after changing the CT attenuation correction (CT-AC) in a stepwise manner. Methods We enrolled 72 patients (Male 36, Female 36) with normal coronary arteries according to findings of invasive coronary angiography or CT-angiography within three months after a SPECT/CT study. Projection images were reconstructed at CT-AC values of (-), 40, 60, 80 and 100 % using a CT number conversion program according to our definition and analyzed using polar maps according to sex. Results CT attenuation corrected segments were located from the mid-and apical-inferior spread through the midand apical-septal regions and finally to the basal-anterior and basal-and mid-lateral regions in males, and from the mid-inferior region through the mid-septal and mid-anterior, and mid-lateral regions in females as the CT-AC values increased. Segments with maximal mean counts shifted from the apical-anterior to mid-anterolateral region under both stress and rest conditions in males, whereas such segments shifted from the apical-septal to the mid-anteroseptal region under both stress and rest conditions in females. Conclusions We clarified which part of the myocardium and to which degree CT-AC affects it in adenosine-stress thallium-201 myocardial perfusion SPECT/CT-IQ.SPECT images by changing the CT-AC value stepwise. We also identified sex-specific shifts of segments with maximal mean counts that changed as CT-AC values increased.
引用
收藏
页码:256 / 267
页数:12
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