Towards a complete description of the microRNA complement of animal genomes

被引:67
作者
Brennecke, J [1 ]
Cohen, SM [1 ]
机构
[1] European Mol Biol Lab, D-69117 Heidelberg, Germany
关键词
D O I
10.1186/gb-2003-4-9-228
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Recent cloning and computational studies have sought to catalog all the microRNA genes encoded in animal genomes. Here, we highlight recent advances in identifying Caenorhabditis elegans and Drosophila melanogaster microRNAs.
引用
收藏
页数:3
相关论文
共 26 条
[1]   A uniform system for microRNA annotation [J].
Ambros, V ;
Bartel, B ;
Bartel, DP ;
Burge, CB ;
Carrington, JC ;
Chen, XM ;
Dreyfuss, G ;
Eddy, SR ;
Griffiths-Jones, S ;
Marshall, M ;
Matzke, M ;
Ruvkun, G ;
Tuschl, T .
RNA, 2003, 9 (03) :277-279
[2]   MicroRNAs and other tiny endogenous RNAs in C-elegans [J].
Ambros, V ;
Lee, RC ;
Lavanway, A ;
Williams, PT ;
Jewell, D .
CURRENT BIOLOGY, 2003, 13 (10) :807-818
[3]   The small RNA profile during Drosophila melanogaster development [J].
Aravin, AA ;
Lagos-Quintana, M ;
Yalcin, A ;
Zavolan, M ;
Marks, D ;
Snyder, B ;
Gaasterland, T ;
Meyer, J ;
Tuschl, T .
DEVELOPMENTAL CELL, 2003, 5 (02) :337-350
[4]   Role for a bidentate ribonuclease in the initiation step of RNA interference [J].
Bernstein, E ;
Caudy, AA ;
Hammond, SM ;
Hannon, GJ .
NATURE, 2001, 409 (6818) :363-366
[5]   siRNAs can function as miRNAs [J].
Doench, JG ;
Petersen, CP ;
Sharp, PA .
GENES & DEVELOPMENT, 2003, 17 (04) :438-442
[6]   Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells [J].
Elbashir, SM ;
Harborth, J ;
Lendeckel, W ;
Yalcin, A ;
Weber, K ;
Tuschl, T .
NATURE, 2001, 411 (6836) :494-498
[7]   Computational and experimental identification of C-elegans microRNAs [J].
Grad, Y ;
Aach, J ;
Hayes, GD ;
Reinhart, BJ ;
Church, GM ;
Ruvkun, G ;
Kim, J .
MOLECULAR CELL, 2003, 11 (05) :1253-1263
[8]   An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells [J].
Hammond, SM ;
Bernstein, E ;
Beach, D ;
Hannon, GJ .
NATURE, 2000, 404 (6775) :293-296
[9]   A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA [J].
Hutvágner, G ;
McLachlan, J ;
Pasquinelli, AE ;
Bálint, É ;
Tuschl, T ;
Zamore, PD .
SCIENCE, 2001, 293 (5531) :834-838
[10]   A microRNA in a multiple-turnover RNAi enzyme complex [J].
Hutvágner, G ;
Zamore, PD .
SCIENCE, 2002, 297 (5589) :2056-2060