Refractory epilepsy and deep brain stimulation

被引：31

作者：

Pereira, Erlick A. C. ^{[1
]}

Green, Alexander L.

Stacey, Richard J.

Aziz, Tipu Z.

机构：

[1] Univ Oxford, Nuffield Dept Surg, Oxford OX3 9DU, England

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2012年 / 19卷 / 01期

基金：

英国医学研究理事会;

关键词：

Deep brain stimulation; Epilepsy; Extratemporal lobe epilepsy; Generalised epilepsy; Partial epilepsy; HIGH-FREQUENCY STIMULATION; MULTIPLE SUBPIAL TRANSECTION; CLOSED-LOOP STIMULATION; ELECTRICAL-STIMULATION; INTRACTABLE EPILEPSY; ANTERIOR NUCLEUS; THALAMIC-STIMULATION; SUBTHALAMIC NUCLEUS; DOUBLE-BLIND; CEREBELLAR STIMULATION;

D O I：

10.1016/j.jocn.2011.03.043

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Up to one-third of all patients with epilepsy have epilepsy refractory to medical therapy. Surgical options include temporal lobectomy, focal neocortical resection, stereotactic lesioning and neurostimulation. Neurostimulatory options comprise vagal nerve stimulation, trigeminal nerve stimulation and deep brain stimulation (DBS). DBS enables structures in the brain to be stimulated electrically by an implanted pacemaker after a minimally invasive neurosurgical procedure and has become the therapy of choice for Parkinson's disease refractory to or complicated by drug therapy. Here we review DBS for epilepsy, a powerful emerging treatment in the surgical armamentarium for drug refractory epilepsy, with a focus on extratemporal epilepsy. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：27 / 33

页数：7

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