Multi-residue method for determination of seven neonicotinoid insecticides in grains using dispersive solid-phase extraction and dispersive liquid-liquid micro-extraction by high performance liquid chromatography

被引：150

作者：

Wang, P. ^{[1
]}

Yang, X. ^{[1
,2
]}

Wang, J. ^{[2
]}

Cui, J. ^{[1
]}

Dong, A. J. ^{[1
]}

Zhao, H. T. ^{[1
]}

Zhang, L. W. ^{[1
]}

Wang, Z. Y. ^{[1
]}

Xu, R. B. ^{[1
]}

Li, W. J. ^{[1
]}

Zhang, Y. C. ^{[1
]}

Zhang, H. ^{[1
]}

Jing, J. ^{[1
]}

机构：

[1] Harbin Inst Technol, Sch Food Sci & Engn, Dept Food Sci, Harbin 150090, Heilongjiang Pr, Peoples R China

[2] Chinese Acad Agr Sci, Inst Qual Standard & Testing Technol Agroprod, Key Lab Agroprod Qual & Safety, Beijing 100081, Peoples R China

来源：

FOOD CHEMISTRY | 2012年 / 134卷 / 03期

关键词：

Neonicotinoid insecticides; Multi-residue analysis; Grains; DSPE; DLLME; HPLC; PESTICIDE-RESIDUES; GAS-CHROMATOGRAPHY; MULTIRESIDUE METHOD; DRINKING-WATER; MICROEXTRACTION; VEGETABLES; CLEANUP; SAMPLES; FRUITS; PRODUCTS;

D O I：

10.1016/j.foodchem.2012.03.103

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A method using dispersive solid-phase extraction and dispersive liquid-liquid micro-extraction cleanup followed by high performance liquid chromatography (HPLC) has been established for determination of seven neonicotinoid insecticides residues in grains including brown rice, maize, millet and oat. Based on an appraisal of the characteristics of HPLC, validation experiments were conducted for seven neonicotinoid insecticides. In the method, dispersive solid-phase extraction was carried out using PSA and bonded C-18 coupled with graphitised carbon black with acetonitrile as the eluted solvent. In the linear range of each pesticide, the correlation coefficient was R-2 >= 0.99. At the low, medium and high three fortification levels of 0.05-0.8 mg kg(-1), recoveries fell within 76-123%. The relative standard deviation was between 0.9% and 12.6% for seven neonicotinoid pesticides. Low limits of detection (0.002-0.005 mg kg(-1)) and quantification (0.007-0.018 mg kg(-1)) were readily achieved with this method for all tested pesticides. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1691 / 1698

页数：8

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