Targeting female hormone receptors as cervical cancer therapy

被引:24
作者
Chung, Sang-Hyuk [1 ]
机构
[1] Univ Houston, Dept Biol & Biochem, Ctr Nucl Receptors & Cell Signaling, Houston, TX 77204 USA
关键词
human papillomavirus; estrogen receptor alpha; progesterone receptor; cervical cancer; hormonal therapy; ESTROGEN-RECEPTOR; PROGESTERONE-RECEPTOR; ALPHA; WOMEN;
D O I
10.1016/j.tem.2015.06.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
While preventive methods for cervical cancer are effective, available therapies for advanced cervical cancers are ineffective. New experimental evidence points to weaknesses of prior studies and provides fresh molecular insights on the opposing roles of estrogen receptor alpha (ER alpha) and the progesterone receptor (PR) that may be translated into valuable treatments for a subset of cervical cancers.
引用
收藏
页码:399 / 401
页数:3
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