A New Triterpenoid Alkaloid from Buxus sempervirens

被引：3

作者：

Yan, Yu-Xin ^{[1
,2
]}

Sun, Yun ^{[1
]}

Chen, Jian-Chao ^{[1
]}

Su, Jia ^{[1
]}

Li, Yan ^{[1
]}

Qiu, Ming-Hua ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2011年 / 66卷 / 10期

关键词：

Buxus sempervirens; Triterpenoid Alkaloid; 16-Deacetoxy-hyrcamine; Cytotoxicity; ALCALOIDES STEROIDIQUES; CYCLOBUXOXAZINE;

D O I：

10.5560/ZNB.2011.66b1076

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new triterpenoid alkaloid, 16-deacetoxy-hyrcamine (1), together with six analogs, was isolated from the leaves and stems of Buxus sempervirens. Their structures were elucidated based on spectral methods and by comparison of the spectral data with those reported previously. All isolated compounds were evaluated for their growth inhibitory activity against human cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480. Compounds 1-4 and 6 showed modest cytotoxic activity against A-549, MCF-7, and SW480.

引用

页码：1076 / 1078

页数：3

共 13 条

[1]

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