Diagnosis of Multidrug-Resistant Pathogens of Pneumonia

被引:9
作者
Sfeir, Maroun M. [1 ]
机构
[1] Univ Connecticut, Hlth Ctr, Dept Pathol & Lab Med, Farmington, CT 06030 USA
关键词
pneumonia; antimicrobial resistance; multidrug resistant bacteria; phenotypic tests; molecular assays; VENTILATOR-ASSOCIATED PNEUMONIA; INFECTIOUS-DISEASES SOCIETY; SPECTRUM-BETA-LACTAMASE; STENOTROPHOMONAS-MALTOPHILIA; BRONCHOALVEOLAR LAVAGE; RESPIRATORY-TRACT; DRUG-RESISTANCE; MANAGEMENT; RECOVERY; THERAPY;
D O I
10.3390/diagnostics11122287
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hospital-acquired pneumonia and ventilator-associated pneumonia that are caused by multidrug resistant (MDR) pathogens represent a common and severe problem with increased mortality. Accurate diagnosis is essential to initiate appropriate antimicrobial therapy promptly while simultaneously avoiding antibiotic overuse and subsequent antibiotic resistance. Here, we discuss the main conventional phenotypic diagnostic tests and the advanced molecular tests that are currently available to diagnose the primary MDR pathogens and the resistance genes causing pneumonia.
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页数:14
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