BiCl3 promoted aza-Prins type cyclization:: a rapid and efficient synthesis of 2,4-disubstituted piperidines

被引：69

作者：

Murty, M. S. R. ^{[1
]}

Ram, Kesur R. ^{[1
]}

Yadav, J. S. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 07期

关键词：

homoallyl amines; aza-Prins-cyclization; BiCl3; piperidines;

D O I：

10.1016/j.tetlet.2007.12.072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several N-protected homoallyl amines and epoxides were subjected to an aza-Prins cyclization. A rapid and efficient BiCl3 promoted stereoselective synthesis of trans-2,4-disubstituted piperidine derivatives was achieved. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1141 / 1145

页数：5

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