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- [1] Discovery of novel dual action Src kinase inhibitors demonstrating anti-resorptive and bone formation activities in vitro and in vivo.JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S377 - S377Xing, LWang, YSundaramoorthi, RKeenan, TMetcalf, CShakespeare, WBohacek, Rvan Schravendijk, MRYamashita, TSheu, TPuzas, EDalgarno, DIuliucci, JSawyer, TBoyce, BF
- [2] Discovery and SAR of a novel series of Src kinase inhibitors.ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U546 - U546Allen, DPrescott, JPham, PPlunkett, MJVirgilio, AABui, M
- [3] Development of a novel bone-targeted Src tyrosine kinase, inhibitor AP23451 having potent in vitro and in vivo anti-resorptive properties.JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S159 - S159Boyce, BFShakespeare, WXing, LWang, YSundaramoorthi, RKeenan, TMetcalf, CBohacek, Rvan Schravendijk, MRDalgarno, TIuliucci, JSawyer, T
- [4] Design and synthesis of novel bone-targeted SRC tyrosine kinase inhibitor drug discoveryABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 227 : U11 - U11Sundaramoorthi, RShakespeare, WCMetcalf, CAWang, KHLiu, SYBohacek, RSNarula, SSKeats, JAWardwell, SIuliucci, JWeigele, MDalgarno, DCSawyer, TK
- [5] Novel bone-targeted Src tyrosine kinase inhibitor drug discoveryCURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2003, 6 (05) : 729 - 741Shakespeare, WCMetcalf, CAWang, YHSundaramoorthi, RKeenan, TWeigele, MBohacek, RSDalgarno, DCSawyer, TK
- [6] Structure-based design of novel osteophilic therapeutics for bone diseases: Discovery of in vivo effective, bone-targeted SRC tyrosine kinase inhibitorsBIOPOLYMERS, 2003, 71 (03) : 296 - 296Sawyer, TKDalgarno, DBohacek, RShakespeare, WCMetcalf, CAWang, YSundaramoorthi, RKeenan, TNarula, SHatada, Mvan Schravendijk, MRIuliucci, JWeigele, MChorev, MAlexander, JRosenblatt, MBain, SShen, VXing, LBoyce, BF
- [7] SAR of carbon-linked, 2-substituted purines:: synthesis and characterization of AP23451 as a novel bone-targeted inhibitor of Src tyrosine kinase with in vivo anti-resorptive activityCHEMICAL BIOLOGY & DRUG DESIGN, 2008, 71 (02) : 97 - 105Shakespeare, William C.Wang, YihanBohacek, RegineKeenan, TerrySundaramoorthil, RajiMetcalf, Chet, IIIDilaurol, AnneRoeloffzen, SonyaLiu, ShuangyingSaltmarsh, JenniferParamanathan, GuruDalgarnol, DavidNarulal, SurinderPradeepan, Selvivan Schravendijk, Marie RoseKeats, JeffRam, MaryLiou, ShuennAdams, SusanWardwell, ScottBogus, JulieLuliucci, JohnWeigele, ManfredXing, LianpingBoyce, BrendanSawyer, Tomi K.
- [8] Novel bone-targeted Src tyrosine kinase inhibitors prevent bone loss and stimulate osteoblast activity.JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 : S148 - S148Boyce, BXing, LBain, SShen, VLiu, CChen, HWang, YShakespeare, WMetcalf, CSundaramoorthi, RKeenan, TBohacek, Rvan Schravendijk, MRDalgarno, DIuliucci, JWeigele, MSawyer, T
- [9] Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity.JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S516 - S516Sawyer, TShakespeare, WYang, MBohacek, RCerasoli, FStebbins, KSundaramoorthi, RVu, CPradeepan, SMetcalf, CHaraldson, CMerry, TDalgarno, DHatada, Mvan Schravendijk, MViolette, SSmith, JGuan, WBartlett, CIuliucci, JWeigele, M
- [10] Discovery of Novel, Thienopyridine-Based Tyrosine Kinase Inhibitors Targeting Tumorigenic RON Splice VariantsACS MEDICINAL CHEMISTRY LETTERS, 2023, 14 (09): : 1198 - 1207Ryu, HyunKim, HyojinPark, InwonLee, MinkiPark, Yoon SunJin, Dong-HunHur, Sun-chulPark, JunhoLee, Hyunho