Instant inactivation of aerosolized SARS-CoV-2 by dielectric filter discharge

被引：5

作者：

Baek, Ki Ho ^{[1
]}

Jang, Donghwan ^{[2
]}

Kim, Taeyoon ^{[2
]}

Park, Joo Young ^{[1
]}

Kim, Dojoon ^{[3
]}

Ryoo, Sungweon ^{[2
]}

Lee, Seunghun ^{[1
]}

机构：

[1] Korea Inst Mat Sci, Dept Nano Bio Convergence, Chang Won, South Korea

[2] Masan Natl TB Hosp, Clin Res Ctr, Chang Won, South Korea

[3] Purunbit, Siheung Si, Gyeonggi Do, South Korea

来源：

PLOS ONE | 2022年 / 17卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

AIRBORNE TRANSMISSION; OZONE;

D O I：

10.1371/journal.pone.0268049

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This study aimed to evaluate the instant inactivation effect of dielectric filter discharge (DFD) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosols. The filter consisted of one layer of ZrO2 beads covered by aluminum mesh electrodes; this porous structure of DFD part generates filter-type surface discharge and reactive oxygen species. In a closed cylindrical chamber, DFD treated air flow containing SARS-CoV-2 aerosols, primarily composed of particle diameters of <= 1 mu m. A polypropylene melt-blown filter collected the treated bioaerosols for inactivation analysis. Plaque and polymerase chain reaction assays showed that the aerosolized SARS-CoV-2 that passed through the filter were more than 99.84% inactivated with degradation of SARS-CoV-2 genes (ORF1ab and E). However, ozone exposure without DFD passage was not found to be effective for bioaerosol inactivation in plaque assay.

引用

页数：11

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