Schiglautone A, a New Tricyclic Triterpenoid with a Unique 6/7/9-Fused Skeleton from the Stems of Schisandra glaucescens

被引:33
作者
Meng, Fan-Yu [1 ]
Sun, Jia-Xiang [1 ]
Li, Xue [1 ]
Yu, Heng-Yi [1 ]
Li, Shu-Ming [2 ]
Ruan, Han-Li [1 ]
机构
[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Fac Pharm, Wuhan 430030, Peoples R China
[2] Univ Marburg, Inst Pharmaceut Biol & Biotechnol, D-35037 Marburg, Germany
关键词
HIGHLY OXYGENATED NORTRITERPENOIDS; DILACTONES; ACID;
D O I
10.1021/ol200188n
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Schiglautone A (1), a unique 6/7/9-fused tricyclic carbon backbone triterpenold, was Isolated from the stems of Schisandra glaucescens. Its structure was determined on the basis of spectroscopic analysis and single-crystal X-ray crystallography. A hypothetical biosynthetic pathway of 1 was postulated.
引用
收藏
页码:1502 / 1505
页数:4
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