Drug Delivery Using Nanoparticle-Stabilized Nanocapsules

被引：110
|
作者：
Yang, Xiao-Chao [1 ,2 ]
Samanta, Bappaditya [1 ]
Agasti, Sarit S. [1 ]
Jeong, Youngdo [1 ]
Zhu, Zheng-Jiang [1 ]
Rana, Subinoy [1 ]
Miranda, Oscar R. [1 ]
Rotello, Vincent M. [1 ]
机构：
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
[2] Third Mil Med Univ, Coll Biomed Engn & Med Imaging, Chongqing 400030, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 02期
关键词：
drug delivery; gold nanoparticles; interfacial energy; nanocapsules; supramolecular interactions; POLYELECTROLYTE MICROCAPSULES; MAGNETIC COLLOIDOSOMES; GOLD NANOPARTICLES; CROSS-LINKING; INTERFACES; CAPSULES; CELLS; WATER; PERMEABILITY; NANOREACTORS;
D O I：
10.1002/anie.201005662
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Small but mighty: Current methods for generating oil-in-water emulsions provide nanoparticle-stabilized capsules (NPSCs) that are too large for efficient delivery. Electrostatic and hydrogen-bonding interactions were combined to create stable NPSCs with diameters of around 100-nm. Their potential as delivery vehicles was demonstrated through dye studies with HeLa cells. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：477 / 481
页数：5
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