Tetralogy of Fallot: 3D Velocity-encoded MR Imaging for Evaluation of Right Ventricular Valve Flow and Diastolic Function in Patients after Correction

被引：44
作者：
van der Hulst, Annelies E. [1 ]
Westenberg, Jos J. M. [2 ]
Kroft, Lucia J. M. [2 ]
Bax, Jeroen J. [3 ]
Blom, Nico A. [1 ]
de Roos, Albert [2 ]
Roest, Arno A. W. [1 ]
机构：
[1] Leiden Univ Med Ctr, Div Pediat Cardiol, Dept Pediat, NL-2300 RC Leiden, Netherlands
[2] Leiden Univ Med Ctr, Dept Radiol, NL-2300 RC Leiden, Netherlands
[3] Leiden Univ Med Ctr, Dept Cardiol, NL-2300 RC Leiden, Netherlands
来源：
RADIOLOGY | 2010年 / 256卷 / 03期
关键词：
MAGNETIC-RESONANCE; PULMONARY REGURGITATION; RESTRICTIVE PHYSIOLOGY; REPAIRED TETRALOGY; FOLLOW-UP; RECOMMENDATIONS; QUANTIFICATION; CHILDREN; ACCURATE;
D O I：
10.1148/radiol.10092269
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Purpose: To evaluate three-dimensional (3D) velocity-encoded (VE) magnetic resonance (MR) imaging, as compared with two-dimensional (2D) VE MR imaging, for assessment of pulmonary valve (PV) and tricuspid valve (TV) flow, with planimetry as the reference standard, and to evaluate diastolic function in patients with a corrected tetralogy of Fallot (TOF). Materials and Methods: Local institutional review board approval was obtained, and patients or their parents gave informed consent. Twenty-five patients with a corrected TOF (12 male, 13 female; mean age, 13.1 years +/- 2.7 [standard deviation]; age range, 8-18 years) and 19 control subjects (12 male, seven female; mean age, 14.1 years +/- 2.4; age range, 8-18 years) underwent planimetric MR imaging, 2D VE MR imaging, and 3D VE MR imaging for TV and PV flow evaluation. For evaluation of diastolic function, PV and TV flow were summated. Data were analyzed by using linear regression analysis, paired and unpaired t testing, and Bland-Altman plots. Results: Strong correlations between the 2D VE MR and 3D VE MR measurements of PV flow (for forward flow: r = 0.87, P < .01; for backward fl ow: r = 0.97, P < .01) were observed. With PV effective fl ow as a reference, 3D TV effective fl ow measurements were more accurate than 2D TV effective fl ow measurements: In patients, the mean 2D TV effective fl ow versus 2D PV effective fl ow difference was 17.6 mL +/- 11 (P < .001), and the mean 3D TV effective fl ow versus 3D PV effective fl ow difference was - 1.2 mL +/- 4.7 (P = .22). Diastolic functional impairment in patients could be detected at 3D VE MR imaging diastolic assessment. Conclusion: Three-dimensional VE MR imaging is accurate for PV fl ow assessment and is more accurate than 2D VE MR imaging for TV fl ow evaluation. Assessment of diastolic function with 3D VE MR imaging can facilitate ongoing research of diastolic dysfunction in patients with a corrected TOF.
引用
收藏
页码：724 / 734
页数：11
相关论文
共 32 条
[1]   Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging [J].
Alfakih, K ;
Plein, S ;
Bloomer, T ;
Jones, T ;
Ridgway, J ;
Sivananthan, M .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2003, 18 (01) :25-32
[2]   STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].
BLAND, JM ;
ALTMAN, DG .
LANCET, 1986, 1 (8476) :307-310
[3]   Pulmonary regurgitation: not a benign lesion [J].
Bouzas, B ;
Kilner, PJ ;
Gatzoulis, MA .
EUROPEAN HEART JOURNAL, 2005, 26 (05) :433-439
[4]   FACTORS INFLUENCING THE ACCURACY AND PRECISION OF VELOCITY-ENCODED PHASE IMAGING [J].
BUONOCORE, MH ;
BOGREN, H .
MAGNETIC RESONANCE IN MEDICINE, 1992, 26 (01) :141-154
[5]   Right ventricular restrictive physiology in repaired tetralogy of Fallot is associated with smaller respiratory variability [J].
Choi, Jae Young ;
Kwon, Hae Sik ;
Yoo, Byung Won ;
Shin, Jae Il ;
Sui, Jun Hee ;
Park, Han Ki ;
Park, Young Hwan .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2008, 125 (01) :28-35
[6]   Comparison of Accuracy of Axial Slices Versus Short-Axis Slices for Measuring Ventricular Volumes by Cardiac Magnetic Resonance in Patients With Corrected Tetralogy of Fallot [J].
Fratz, Sohrab ;
Schuhbaeck, Annika ;
Buchner, Christine ;
Busch, Raymonde ;
Meierhofer, Christian ;
Martinoff, Stefan ;
Hess, John ;
Stern, Heiko .
AMERICAN JOURNAL OF CARDIOLOGY, 2009, 103 (12) :1764-1769
[7]   Biventricular long axis function after repair of tetralogy of Fallot [J].
Gatzoulis, MA ;
Norgard, G ;
Redington, AN .
PEDIATRIC CARDIOLOGY, 1998, 19 (02) :128-132
[8]   Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study [J].
Gatzoulis, MA ;
Balaji, S ;
Webber, SA ;
Siu, SC ;
Hokanson, JS ;
Poile, C ;
Rosenthal, M ;
Nakazawa, M ;
Moller, JH ;
Gillette, PC ;
Webb, GD ;
Redington, AN .
LANCET, 2000, 356 (9234) :975-981
[9]   MECHANOELECTRICAL INTERACTION IN TETRALOGY OF FALLOT - QRS PROLONGATION RELATES TO RIGHT-VENTRICULAR SIZE AND PREDICTS MALIGNANT VENTRICULAR ARRHYTHMIAS AND SUDDEN-DEATH [J].
GATZOULIS, MA ;
TILL, JA ;
SOMERVILLE, J ;
REDINGTON, AN .
CIRCULATION, 1995, 92 (02) :231-237
[10]   RIGHT-VENTRICULAR DIASTOLIC FUNCTION 15 TO 35 YEARS AFTER REPAIR OF TETRALOGY OF FALLOT - RESTRICTIVE PHYSIOLOGY PREDICTS SUPERIOR EXERCISE PERFORMANCE [J].
GATZOULIS, MA ;
CLARK, AL ;
CULLEN, S ;
NEWMAN, CGH ;
REDINGTON, AN .
CIRCULATION, 1995, 91 (06) :1775-1781
1234