An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring

被引:129
作者
Chen, Yen-Po [1 ]
Jeon, Dongsuk [1 ]
Lee, Yoonmyung [1 ,2 ]
Kim, Yejoong [1 ]
Foo, Zhiyoong [1 ]
Lee, Inhee [1 ]
Langhals, Nicholas B. [3 ]
Kruger, Grant [1 ]
Oral, Hakan [3 ]
Berenfeld, Omer [3 ]
Zhang, Zhengya [1 ]
Blaauw, David [1 ]
Sylvester, Dennis [1 ]
机构
[1] Univ Michigan, Ann Arbor, MI 48105 USA
[2] Sungkyunkwan Univ, Suwon 110745, South Korea
[3] Univ Michigan Hlth Syst, Ann Arbor, MI 48105 USA
基金
美国国家科学基金会;
关键词
Analog front-end (AFE); asynchronous logic; capacitive feedback chopper stabilized instrumental amplifier (CCIA); electrocardiography (ECG); fast Fourier transform (FFT); implantable system; kickback noise; minimum energy point (MEP); mm(3); SKIN-ELECTRODE IMPEDANCE; SAR ADC; CMOS; AMPLIFIER; HZ;
D O I
10.1109/JSSC.2014.2364036
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.
引用
收藏
页码:375 / 390
页数:16
相关论文
共 35 条
[1]  
Do AT, 2012, IEEE INT NEW CIRC, P525, DOI 10.1109/NEWCAS.2012.6329072
[2]  
[Anonymous], 2002, ANSIAAMIEC13
[3]   SKIN-ELECTRODE IMPEDANCE PROBLEMS IN ELECTROCARDIOGRAPHY [J].
BERSON, AS ;
PIPBERGER, HV .
AMERICAN HEART JOURNAL, 1968, 76 (04) :514-+
[4]  
Chae M., 2008, 2008 IEEE International Solid State Circuits Conference, ISSCC, P146
[5]  
Dai Zhang, 2012, ESSCIRC 2012 - 38th European Solid State Circuits Conference, P369, DOI 10.1109/ESSCIRC.2012.6341331
[6]  
Deepu CJ, 2013, IEEE ASIAN SOLID STA, P145, DOI 10.1109/ASSCC.2013.6691003
[7]  
DENISON T, 2007, IEEE INT SOL STAT CI, P162
[8]   Circuit techniques for reducing the effects of op-amp imperfections: Autozeroing, correlated double sampling, and chopper stabilization [J].
Enz, CC ;
Temes, GC .
PROCEEDINGS OF THE IEEE, 1996, 84 (11) :1584-1614
[9]   A 1.8 μW 60 nV/√Hz Capacitively-Coupled Chopper Instrumentation Amplifier in 65 nm CMOS for Wireless Sensor Nodes [J].
Fan, Qinwen ;
Sebastiano, Fabio ;
Huijsing, Johan H. ;
Makinwa, Kofi A. A. .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2011, 46 (07) :1534-1543
[10]  
Han D, 2013, ISSCC DIG TECH PAP I, V56, P290, DOI 10.1109/ISSCC.2013.6487739